Super-resolution Ultrasound Imaging

Christensen-Jeffries, Kirsten; Couture, Olivier; Dayton, Paul A.; Eldar, Yonina C.; Hynynen, Kullervo; Kießling, Fabian; O’Reilly, Meaghan A.; Pinton, Gianmarco; Schmitz, Georg; Tang, Meng‐Xing; Tanter, Mickaël; Sloun, Ruud J. G. van

doi:10.1016/j.ultrasmedbio.2019.11.013

Cited by 317 publications

(207 citation statements)

References 166 publications

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“…Super-resolution ultrasound imaging is a new technique which allows, after introducing a microbubbles visualization of microvascularity at a resolution of tens of microns [111,112]. A major advantage over classic high-frequency techniques, where higher frequency means lower penetration, is that with superresolution ultrasound there is no penetration trade-off associated with higher frequencies [111]. This may allow in the future precise mapping of placental vasculature or fetal brain, for instance in early stages of fetal growth restriction.…”

Section: Super-resolution Ultrasoundmentioning

confidence: 99%

Obstetric ultrasound: where are we and where are we going?

Abramowicz

2021

Ultrasonography

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Ultrasonography. 2020 Aug 25. Epub ahead of print Diagnostic ultrasound (DUS) is, arguably, the most common technique used in obstetrical practice. From A mode, first described by Ian Donald for gynecology in the late 1950s, to B mode in the 1970s, real-time and gray-scale in the early 1980s, Doppler a little later, sophisticated color Doppler in the 1990s and three dimensional/four-dimensional ultrasound in the 2000s, DUS has not ceased to be closely associated with the practice of obstetrics. The latest innovation is the use of artificial intelligence which will, undoubtedly, take an increasing role in all aspects of our lives, including medicine and, specifically, obstetric ultrasound. In addition, in the future, new visualization methods may be developed, training methods expanded, and workflow and ergonomics improved.

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Section: Super-resolution Ultrasoundmentioning

confidence: 99%

Obstetric ultrasound: where are we and where are we going?

Abramowicz

2021

Ultrasonography

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“…Moreover, the dependence of CEST contrast on a variety of experimental parameters constitutes a challenge for the reproducibility of CEST results [70]. 13…”

Section: Chemical Exchange Saturation Transfermentioning

confidence: 99%

“…Another promising approach toward metabolic imaging is 13 C hyperpolarized MRI, for which a special preparation step results in highly increased signal from 13 C contrast agents. Among these, [ [1][2][3][4][5][6][7][8][9][10][11][12][13] C]pyruvate is evaluated in clinical trials for the visualization of metabolic changes during treatment of prostate cancer (. Fig.…”

Section: Hyperpolarized Magnetic Resonance Imagingmentioning

confidence: 99%

Emerging methods in radiology

et al. 2020

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Imaging modalities have developed rapidly in recent decades. In addition to improved resolution as well as whole-body and faster image acquisition, the possibilities of functional and molecular examination of tissue pathophysiology have had a decisive influence on imaging diagnostics and provided ground-breaking knowledge. Many promising approaches are currently being pursued to increase the application area of devices and contrast media and to improve their sensitivity and quantitative informative value. These are complemented by new methods of data processing, multiparametric data analysis, and integrated diagnostics. The aim of this article is to provide an overview of technological innovations that will enrich clinical imaging in the future, and to highlight the resultant diagnostic options. These relate to the established imaging methods such as CT, MRI, ultrasound, PET, and SPECT but also to new methods such as magnetic particle imaging (MPI), optical imaging, and photoacoustics. In addition, approaches to radiomic image evaluation are explained and the chances and difficulties for their broad clinical introduction are discussed. The potential of imaging to describe pathophysiological relationships in ever increasing detail, both at whole-body and tissue level, can in future be used to better understand the mechanistic effect of drugs, to preselect patients to therapies, and to improve monitoring of therapy success. Consequently, the use of interdisciplinary integrated diagnostics will greatly change and enrich the profession of radiologists.

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“…Ultrasound super-resolution imaging (SRI) has been studied by various research groups over the last years [1]- [7]. The approach employs detection and tracking of microbubble (MB) contrast agents to visualize the micro-vasculature including the capillary network.…”

Section: Introductionmentioning

confidence: 99%

Tracking Performance in Ultrasound Super-Resolution Imaging

Taghavi

Andersen

Hoyos

et al. 2020

2020 IEEE International Ultrasonics Symposium (IUS)

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Tracking plays an important role in super-resolution (SR) ultrasound imaging, as it improves the quality and sharpness of the final SR images. Moreover, tracking enables quantification of clinically important parameters, such as blood flow velocity. However, the tracking performance degrades in the presence of complex particle patterns and localization uncertainty due to noise and motion. This work presents and discusses multiple approaches for tracking evaluation and compares a nearestneighbor (NN) with a Kalman tracker through simulations and an in vivo experiment. It is shown that in the presence of a localization uncertainty with a standard deviation (SD) of λ /5, the bias and SD of the velocity estimates reach-1.04 ± 0.9 mm/s and-0.12 ± 0.72 mm/s in the NN and Kalman tracker, respectively (relative to the peak velocity of 10 mm/s). The precision of individual track positions is estimated for an in vivo experiment as 37.95 ± 21.37 µm and 23.9 ± 11.82 µm for the NN and Kalman trackers, respectively. The results indicate that the Kalman tracker achieves a better velocity estimation and reduces localization uncertainty.

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Super-resolution Ultrasound Imaging

Cited by 317 publications

References 166 publications

Obstetric ultrasound: where are we and where are we going?

Obstetric ultrasound: where are we and where are we going?

Emerging methods in radiology

Tracking Performance in Ultrasound Super-Resolution Imaging

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