Super-resolution imaging by microsphere-assisted optical microscopy

Lin, Qiaowen; Wang, Dayong; Wang, Yunxin; Rong, Lü; Zhao, Jie; Guo, Sha; Wang, Minchao

doi:10.1007/s11082-016-0833-2

Cited by 15 publications

(6 citation statements)

References 16 publications

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“…In this case, the coupling efficiency of the evanescent wave by the microsphere appears to be low beyond a distance z = 400 nm. In Figure 2b, the far-field relative radiated power was estimated by considering the incident power P 0 through the radius of the estimated interaction area [21], i.e., √ 2λ 0 h with h, the penetration depth measuring around 125 nm in this configuration (1/|k z |, see Equation ( 1)). The optical power emanating from the top of the microsphere is not null and decreases as distance increases (e.g., 0.9% P 0 at z = 200 nm and 0.1% P 0 at z = 400 nm).…”

Section: Resultsmentioning

confidence: 99%

“…The role of coherence in the imaging process has been pointed out where two point objects need to be out-ofphase in order to be resolved [20]. The role of evanescent waves was first experimentally suggested through a decrease in resolution with an increase in the distance microspheresample [21] and more-recently confirmed using semi-immersed BaTiO 3 microspheres [22]. To our knowledge, the most advanced explanation has been proposed by Zhou et al [23] where whispering-gallery modes excited inside the microsphere by high-spatial frequencies from the object make it possible to contribute to a virtual image resolution.…”

Section: Introductionmentioning

confidence: 99%

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Near- to Far-Field Coupling of Evanescent Waves by Glass Microspheres

et al. 2021

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Through rigorous electromagnetic simulations, the natural coupling of high-spatial-frequency evanescent waves from the near field to the far field by dielectric microspheres is studied in air. The generation of whispering gallery modes inside the microspheres is shown independently of any resonance. In addition, the conversion mechanism of these evanescent waves into propagating waves is analysed. This latter point leads to key information that allows a better physical understanding of the super-resolution phenomenon in microsphere-assisted microscopy where sub-diffraction-limit revolving power is achieved.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Near- to Far-Field Coupling of Evanescent Waves by Glass Microspheres

et al. 2021

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“…For the 30 μm microsphere at the visible band, the measured field of view is proportional to the square root of the microsphere diameter [29] and is about 5.5 μm. It could be noted that such a field of view is significantly larger, for example than that covered by the known hyperlenses [30].…”

Section: Oblique Illumination Images In Mesoscale Particle-based Micr...mentioning

confidence: 99%

BaTiO3 microsphere assisted imaging of erythrocytes by light structuring photonic hook

Minin,

et al. 2024

International Academic Conference on Optics and Photonics (IACOP 2023)

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The red blood cells, the role of which is difficult to underestimate in life and biology, were usually chosen as a sample for observation in an optical microscope. In this paper, we show that using optical microscopy based on high-index spherical mesoscale particles with a refractive index of 1.9, generating a non-evanescent curved light beam with subwavelength structures -so-called a structure light photonic hook by partial illumination conditions, it is possible to study the transformation dynamics of an erythrocyte into an echinocyte. Examples of images are presented. The findings in this manuscript have promising application prospects in nanomanipulation, biology, and medicine.

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“…Nonlinear SIM (NSIM) is put forward by applying photoswitchable protein instead of fluorescence saturation for super-resolution imaging [29,30,31,32]. The sample frequency spectrum and the recovery image in Fig.…”

Section: Comparison With Nonlinear Simmentioning

confidence: 99%

Tilt illumination for structured illumination imaging

et al. 2021

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To achieve super-resolution imaging, the information in higher frequency of the observed sample is collected by illuminating with a structure beam for a limited optical transfer function (OTF). In this paper, tilt illumination mode is introduced to structured illumination microscopy (SIM) for enhancing lateral resolution. More sample spectrum more than traditional SIM, can be obtained by detector. Thus, SIM with tilt illumination can be improved at the aspect of lateral imaging resolution.

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Super-resolution imaging by microsphere-assisted optical microscopy

Cited by 15 publications

References 16 publications

Near- to Far-Field Coupling of Evanescent Waves by Glass Microspheres

Near- to Far-Field Coupling of Evanescent Waves by Glass Microspheres

BaTiO3 microsphere assisted imaging of erythrocytes by light structuring photonic hook

Tilt illumination for structured illumination imaging

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