Super macroporous poly(N‐isopropyl acrylamide) cryogel for separation purpose

Abstract

Polymers that can respond reversibly by changing their physical or chemical properties are recognized as stimuli-responsive polymers. The renowned temperature-sensitive polymer is poly(N-isopropyl acrylamide) (p(NIPAM)), and here, homopolymeric supermacroporous p(NIPAM)) cryogel was synthesized via cryopolymerization technique at cryogenic condition (below melting point of solvent, −18°C). Then, the prepared p(NIPAM) cryogel was characterized via scanning electron microscopy, Fourier transform infrared radiation spectrometer, and thermogravimetric analyzer.The lower critical solution temperature (LCST) value of the prepared p(NIPAM) cryogel was determined from % swelling equilibrium swellings at various temperatures, 20, 25, 30, 35, 40, 45, and 50°C, respectively. Furthermore, the pore volume and porosity of p(NIPAM) cryogels were compared below and above the LCST values.Finally, the separation capability of p(NIPAM) cryogels for some molecules such as tannic acid, gallic acid, nicotine (N), and caffeine (C) was investigated at the below and above the LCST values. KEYWORDS column filler material, p(NIPAM) cryogel, smart cryogel/hydrogel, temperature-responsive super porous cryogel

Cryostructuring of Polymeric Systems. 50.† Cryogels and Cryotropic Gel-Formation: Terms and Definitions

“…Typical examples of macroporous cryogenically-structured polymeric matrices are the aforementioned non-covalent poly(vinyl alcohol) cryogels [26,43,44,45,46,47,48,49,52,53,54], the amylopectin-based cryogels [55], certain locust-bean-gum-based cryogels [56]. Some well-known examples of the wide-porous/supermacroporous cryogels and cryostructurates are those based on the cross-linked poly(acrylamide) [57,58,59,60,61,62,63], thermoresponsive cross-linked poly( N , N -diethylacrylamide) [64], poly(N-isopropylacrylamide) [65,66,67,68,69,70] and poly( N -vinylcaprolactram) [71], radiation- and chemically-polymerized 2-hydroxyethyl methacrylate [72,73,74,75], covalently cross-linked proteins [39,40,76,77,78,79,80], polysaccharides [21,41,55,56,81,82,83,84,85,86,87] and nucleic acids [88,89], various synthetic high polymers [4,21,35,37,90,91,92,93,94], as well as numerous physical and ionic cryogels and cryostructurates [4,…”

Influence of carboxyl and amide groups on in vitro hemocompatibility of sulfonated polypropylene non‐woven fabric

“…21 Therefore, HR reflects the degree of damage a material may cause to erythrocyte, and is regarded as the one of the most important factors for evaluation of the hemocompatibility of materials routinely exposed to blood. 22 It is documented that hemolysis can be classified into three levels, including non-hemolytic (0%-2% of hemolysis), slightly hemolytic (2%-5% of hemolysis), and hemolytic (>5% of hemolysis). 23 Furthermore, the materials can be recognized as hemocompatible when HR is less than 5%.…”

One‐step preparation of poly(NIPAM‐pyrrole) electroconductive composite hydrogel and its dielectric properties

“…The applicability of hydrogels in a range of biomedical applications; such as, biosensors, drug release and tissue engineering, motivates researchers to generate new ideas on 3D networks that include newly adapted features such as thermal, optical, and electrical conductivities 2 . Poly(N‐isopropyl acrylamide) (poly(NIPAM), which is one of the most frequently used polymers in hydrogel synthesis, has hydrophobic groups, such as, propyl, as well as hydrophilic amide groups 3 . Poly(NIPAM) polymer, whose characterization has been successfully illuminated to date as a result of the hydrophilic and hydrophobic groups it contains, is known as the most studied temperature‐sensitive polymer in the literature 4 .…”