<sup>18</sup>F‐sodium fluoride positron emission tomography of the equine distal limb: Exploratory study in three horses

Spriet, Mathieu; Espinosa, Patricia; Kyme, Andre; Phillips, Kathryn; Katzman, Scott A.; Galuppo, Larry D.; Stepanov, Pavel; Beylin, David

doi:10.1111/evj.12719

Cited by 30 publications

(41 citation statements)

References 22 publications

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“…Other adjunctive methods have been explored to overcome the insensitivity of soft tissue evaluation with CT: contrast-enhanced CT (CECT), positron emission tomography, spectral CT, phase contrast x-ray computed tomography and dual energy CT [49][50][51][52][53][54][55][56]. These methods improve upon and expand the physiological information usually limited with standard CT.…”

Section: Computed Tomographymentioning

confidence: 99%

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

Nelson

Kawcak

Barrett

et al. 2018

Equine Veterinary Journal

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Articular cartilage is a critical joint tissue and its evaluation remains a diagnostic challenge in horses. Coupled with a poor capacity for healing, early degenerative changes in articular cartilage are difficult to characterise using routine diagnostic imaging evaluations. Both computed tomography (CT) and magnetic resonance imaging (MRI) provide volumetric joint assessment and highlight morphological and quantitative properties of articular cartilage, improving assessment of this essential tissue. While the use of CT and MRI for joint evaluation is not new, there still remains a shortage of literature and scientific studies on the ability of these methods to evaluate articular cartilage in the horse. This review article summarises current CT and MRI techniques capable of characterising equine articular cartilage, highlights recent advances in these techniques and discusses the numerous methods studied in human subjects that have been minimally investigated in horses. Imaging techniques are presented in terms of their capabilities of offering morphological and quantitative evaluation along with a discussion of their benefits and limitations. Finally, it summarises the current state-of-the-art approaches and identifies unmet clinical imaging needs to propel the advancement of articular cartilage and joint imaging in the horse.

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Section: Computed Tomographymentioning

confidence: 99%

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

Nelson

Kawcak

Barrett

et al. 2018

Equine Veterinary Journal

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“…Scintigraphy is a sensitive imaging modality used to detect areas of stress remodelling , but is limited by poor spatial resolution and two‐dimensional (planar) imaging . Recently, another nuclear medicine modality, positron emission tomography (PET), has become available for equine imaging . Compared with scintigraphy, PET offers cross‐sectional imaging properties and higher spatial resolution.…”

Section: Introductionmentioning

confidence: 99%

¹⁸F‐sodium fluoride positron emission tomography of the racing Thoroughbred fetlock: Validation and comparison with other imaging modalities in nine horses

Spriet

Espinosa‐Mur

Cissell

et al. 2018

Equine Veterinary Journal

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“…The region of insertion of the deep digital flexor tendon (DDFT) onto the coffin bone and collateral ligaments of the distal interphalangeal joint can also be evaluated on the solar view (2,3,7). Current advances in Positron Emission Tomography (PET) with 18 F-NaF in equine diagnostic imaging shows promise in providing additional and valuable information in evaluation of structures in the equine distal limb (19,20). Although this modality utilizes similar nuclear medicine principles seen in standard equine bone scanning, the positrons are emitted at an energy of 511 keV, significantly higher than 99m Tc-MDP, and theoretically the attenuation would be reduced.…”

Section: Discussionmentioning

confidence: 99%

Attenuation From Shoes and Pads in Equine Nuclear Scintigraphy, With Relevance to Solar Views

Walker¹,

Martinelli²,

Rantanen³

et al. 2020

Front. Vet. Sci.

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Nuclear scintigraphy can be beneficial in the investigation of equine lameness and poor performance. Images obtained through the sole allow for better identification of a region of increased radionuclide uptake in the foot. The presence of shoes or pads may affect these images. To determine the degree of radioactive attenuation different types of shoes and pads of different thickness and materials were evaluated by placing the material directly on the gamma camera detector acquiring flood images from a point source. The study compared five different types of shoes from 3 different shoeing materials, steel, aluminum, and polyurethane. This study also assessed 8 different types of pads that were selected based on the subjective densities and variable rigidity of the materials. All types of shoes/pads evaluated caused some degree of attenuation (P < 0.05). Steel shoes of all types cause the most attenuation (54%), followed by aluminum shoes (22%), and the shoes or pads composed primarily of a plastic polymer cause the least amount of attenuation (15%). The results of the study found that pads or shoes cause significant (p < 0.05) attenuation of gamma radiation. Composition, thickness and density characterized mass absorption coefficient, of the material affect the amount of gamma radiation attenuation. Because of the attenuation of gamma radiation, we recommend shoes and pads be removed prior to nuclear scintigraphic examination of the front foot if a solar image is desired, as this attenuation may affect image quality.

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¹⁸F‐sodium fluoride positron emission tomography of the equine distal limb: Exploratory study in three horses

Abstract: F-NaF PET imaging of the equine distal limb provides useful additional information when compared with CT, MRI and scintigraphy and has the potential for both research and clinical applications in the horse. The Summary is available in Chinese - see Supporting information.

Cited by 30 publications

References 22 publications

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

¹⁸F‐sodium fluoride positron emission tomography of the racing Thoroughbred fetlock: Validation and comparison with other imaging modalities in nine horses

Attenuation From Shoes and Pads in Equine Nuclear Scintigraphy, With Relevance to Solar Views

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18F‐sodium fluoride positron emission tomography of the equine distal limb: Exploratory study in three horses

Abstract: F-NaF PET imaging of the equine distal limb provides useful additional information when compared with CT, MRI and scintigraphy and has the potential for both research and clinical applications in the horse. The Summary is available in Chinese - see Supporting information.

Cited by 30 publications

References 22 publications

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

Recent advances in articular cartilage evaluation using computed tomography and magnetic resonance imaging

18F‐sodium fluoride positron emission tomography of the racing Thoroughbred fetlock: Validation and comparison with other imaging modalities in nine horses

Attenuation From Shoes and Pads in Equine Nuclear Scintigraphy, With Relevance to Solar Views

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Product

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¹⁸F‐sodium fluoride positron emission tomography of the equine distal limb: Exploratory study in three horses

¹⁸F‐sodium fluoride positron emission tomography of the racing Thoroughbred fetlock: Validation and comparison with other imaging modalities in nine horses