[<sup>18</sup>F]Fluorodeoxyglucose Positron Emission Tomography–Guided Therapy in Metastatic Adrenocortical Carcinoma: An Illustrative Case

Chuang, Hubert H.; Denız, Ferhat; Sircar, Kanishka; Jiménez, Camilo; Celis, Carlos R.; Wood, Christopher G.; Habra, Mouhammed Amir

doi:10.1200/jco.2011.40.6710

Cited by 5 publications

(1 citation statement)

References 15 publications

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“…In the study by Hubert et al that evaluated the role of PET/CT in the evaluation of response to therapy in metastatic disease, the evaluation of metastatic disease using PERCIST provided a complete metabolic response and PET/CT provided a 51% response rate. Their study found that PET/CT was a sensitive diagnostic tool in monitoring response to therapy in ACC [ 15 ]. In the literature, the sensitivity of PET/CT in diagnosing ACC was 100%, specificity was 98%, and positive predictive value (PPV), negative predictive value (NPV), and accuracy were 97%, 100%, and 86–96%, respectively [ 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

Role of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in restaging of adrenocortical carcinoma

Ozturk

2024

Rep Pract Oncol Radiother.

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Background The objective was to retrospectively evaluate the contribution of fluorodeoxyglucose [ 18 F] positron emission tomography/computed tomography ( 18 FDG-PET/CT) to the re-staging of adrenocortical carcinoma (ACC). Materials and methods A total of 16 patients (10 males and 6 females), who underwent adrenalectomy due to adrenocortical carcinoma and 18 FDG-PET/CT scan to re-stage the tumor between July 2007 and April 2013, were included in the present study. The mean age was 53.37 ± 13.91 years (min: 30, max: 74) The patients were required to fast for six hours prior to scanning, and whole-body PET scanning from the skull base to the upper thighs was performed approximately 1 h after the intravenous injection of 555 MBq of F-18 FDG. Whole body CT scanning was performed in the cranio-caudal direction. FDG-PET images were reconstructed using CT data for attenuation correction. Suspicious recurrent or metastatic lesions were confirmed by histopathology or clinical follow-up. Results Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 18 FDG-PET/CT were 100%, 83.3%, 90.9%, 83.3%, and 93.7%, respectively. Conclusion 18 FDG-PET/CT detects local recurrence and/or distant metastases with high accuracy in the re-staging of operated adrenocortical carcinoma. It is considered that the procedure could play an important role in treatment decision after the operation and post-operative follow-up and could influence the entire decision-making process.

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Section: Discussionmentioning

confidence: 99%

Role of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in restaging of adrenocortical carcinoma

Ozturk

2024

Rep Pract Oncol Radiother.

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Therapies for Locally Advanced and Metastatic Adrenocortical Carcinoma

Rao

Habra

2016

Management of Adrenal Masses in Children and Adults

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Impact of 18F-FDG PET/CT on the management of adrenocortical carcinoma: analysis of 106 patients

Takeuchi

Balachandran

Habra

et al. 2014

Eur J Nucl Med Mol Imaging

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[¹⁸F]Fluorodeoxyglucose Positron Emission Tomography–Guided Therapy in Metastatic Adrenocortical Carcinoma: An Illustrative Case

Cited by 5 publications

References 15 publications

Role of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in restaging of adrenocortical carcinoma

Role of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in restaging of adrenocortical carcinoma

Therapies for Locally Advanced and Metastatic Adrenocortical Carcinoma

Impact of 18F-FDG PET/CT on the management of adrenocortical carcinoma: analysis of 106 patients

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[18F]Fluorodeoxyglucose Positron Emission Tomography–Guided Therapy in Metastatic Adrenocortical Carcinoma: An Illustrative Case

Cited by 5 publications

References 15 publications

Role of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in restaging of adrenocortical carcinoma

Role of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography in restaging of adrenocortical carcinoma

Therapies for Locally Advanced and Metastatic Adrenocortical Carcinoma

Impact of 18F-FDG PET/CT on the management of adrenocortical carcinoma: analysis of 106 patients

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[¹⁸F]Fluorodeoxyglucose Positron Emission Tomography–Guided Therapy in Metastatic Adrenocortical Carcinoma: An Illustrative Case