¹H and ¹³C NMR structural studies in solution of oxotechnetium(V) complexes with N,N‐bis(2‐mercaptoethyl)‐N′,N′‐diethylethylenediamine and N,N‐bis(2‐mercaptoethyl)‐2‐ethylthioethylamine

Abstract

Institute of Radioisotopes-Radiodiagnostic

Synthesis and Characterization of Rhenium(V) Oxo Complexes withN-[N-(3-Diphenylphosphinopropionyl)glycyl]cysteine Methyl Ester. X-ray Crystal Structure of {ReO[Ph2P(CH2)2C(O)-Gly-Cys-OMe(P,N,N,S)]}

“…These values were consistent with the coupling constants observed in the 1 H NMR, and on the basis of this consideration the signal at 3.83 ppm ( 3 J = 2.1) was assigned to the endo and the signal at 3.24 ppm ( 3 J = 7.9) to the exo proton. The assignments were in accordance with the literature-reported data on oxo−rhenium complexes, indicating that protons spatially close to the oxygen of the ReO are deshielded relative to those remote from the oxygen.…”

Synthesis and Characterization of Oxotechnetium(V) Mixed-Ligand Complexes Containing a Tridentate N-Substituted Bis(2-mercaptoethyl)amine and a Monodentate Thiol

“…The four protons of each moiety are diastereotopic each one resulting in a multiplet. The downfield overlapped multiplets (3.36−4.23 ppm) are assigned to the protons which are close (endo) to the TcO core, while the other two multiplets (2.61−3.42 ppm) are assigned to the protons which are remote (exo) . The protons attached to the C5 of the N-subtituent (Figure ) of the isolated major complexes are found in a deshielded environment at 3.87−4.06 ppm indicating that all have the same configuration ( syn ).…”

Glutathione Interaction with SNS/S Mixed-Ligand Complexes of Oxorhenium(V): Kinetic Aspects and Characterization of the Products

“…Chemical shifts ( δ , ppm) were referenced to TMS for samples run in CDCl 3 and to DSS for samples run in D 2 O. Parameters for the 2D experiments (COSY, HETCOR, NOESY, etc.) have been previously reported. ,,, Elemental analyses for C, H, N, and S were conducted on a Perkin-Elmer 2400/II Automatic Elemental Analyzer. HPLC analyses were performed on a Waters Chromatograph efficient with a 600 solvent delivery system and coupled to a Waters 996 Photodiode Array UV Detector.…”