¹H and ¹³C chemical shifts for acridines: Part XVII. (1,3‐Benzothiazol‐2‐yl)amino‐9(10H)‐acridinone derivatives

Abstract

The 1 H and 13 C NMR resonances for 16 acridin-9(10H)-ones substituted with amino or (1,3-benzothiazol-2-yl)amino groups were completely and unequivocally assigned by the concerted application of gs-COSY, gs-HMQC and gs-HMBC experiments. Evidence for hydrogen bond and amino-imino tautomerism is presented for 1-and 4-substituted acridin-9(10H)-ones.

Differentiation of heterocyclic regioisomers: a combined tandem mass spectrometry and computational study of N‐acridin‐4‐ylbenzylamide and N‐acridin‐2‐yl‐benzylamide

“…The 1 H NMR spectra of the two isomers show an important overlap which has been resolved using 2D correlation experiments (data not shown). NMR chemical shift assignments have been reported for a large number of acridine derivatives 20–22. The analysis of the NMR spectra confirmed the structures of the two derivatives studied in the present work.…”

1H and13C chemical shifts for acridines: part XIX.N,N′-diacylproflavine derivatives

“…10 Figure 1 shows the structures of these compounds. Proton and carbon NMR spectra were recorded in DMSO-d 6 solutions at 300 K using a Bruker Avance DRX 300 spectrometer. Chemical shifts were referenced to DMSO-d 6 : υ 1 H D 2.50 ppm, υ 13 C D 39.6 ppm.…”

“…Proton and carbon NMR spectra were recorded in DMSO-d 6 solutions at 300 K using a Bruker Avance DRX 300 spectrometer. Chemical shifts were referenced to DMSO-d 6 : υ 1 H D 2.50 ppm, υ 13 C D 39.6 ppm. 11 CH n -information for 13 C signals was established by acquisition of DEPT spectra.…”

1H and 13C chemical shifts for 2‐aryl and 2‐N‐arylamino benzothiazole derivatives

“…The temperature of the probe and preamplifier was 30 K. Chemical shifts were referenced Ł Correspondence to: M. Robin 15 Resonance multiplicities for 13 C signals were established via the acquisition of DEPT spectra. For two-dimensional experiments, Brüker microprograms using gradient selection (gs) were applied.…”

“…7 Recently, these compounds were also used as precursors for in vivo imaging ofˇ-amyloid plaques, 8 and for nonlinear optical application. 9 As a part of our program aimed at developing new heterocyclics bearing a thiazole ring, 10 -13 we report in this paper the complete 1 H and 13 C NMR chemical shift assignments using one-and two-dimensional NMR techniques, including DEPT, gs-COSY, gs-HMQC and gs-HMBC, for 2-N-arylamino benzothiazole and 2-aryl benzothiazole derivatives.…”