Sunscreen and Prevention of Skin Aging

Hughes, Maria Celia; Williams, Gail M.; Baker, Peter; Green, Adèle C.

doi:10.7326/0003-4819-158-11-201306040-00002

Cited by 163 publications

(107 citation statements)

References 39 publications

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“…The authors suggested the potential protection against ROS, avoiding skin aging and other diseases [14]. On the other hand, a randomized, controlled and community-based intervention in Australia, including 903 adults, younger than 55 years, identified no additional effect on skin aging of the daily use of 30 mg of b-carotene supplementation during 4.5 years associated with daily use of broad-spectrum sunscreen [8]. The analysis of the food diary filled out by the subjects of this study demonstrated bad dietary habits, with meals at irregular schedules, low intake of fruit and greens, and use of saturated fat and sodium, stemming from Arch Dermatol Res industrialized products, above current recommendations.…”

Section: Discussionmentioning

confidence: 96%

Lycopene not in pill, nor in natura has photoprotective systemic effect

2015

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Carotenoids are endogenous antioxidant agents. It has been reported that oral lycopene reduces immediate erythema induced by ultraviolet B radiation. The objective was to evaluate and compare the photoprotective effect of lycopene in capsule and tomato paste. This was an interventional, randomized, comparative 10-week study that included 20 subjects, divided in two groups: 10 for capsule and 10 for tomato paste intake. Blood samples were collected for serum lycopene dosage by high-performance liquid chromatography. Chromatometer was used to measure minimal erythematous dose 24 h after only ultraviolet B irradiation and the variation of color a (maximum erythema, 24 h after irradiation compared to normal skin). Evaluations were made at baseline and after 4, 8, and 10 weeks. Data were analyzed by ANOVA with repeated measures. Three subjects dropped out after 4 weeks. Serum lycopene demonstrated great variability; significant, higher levels for tomato after 4 weeks (p = 0.027) as compared to capsule and significant increase along the study just for tomato (p = 0.044) were detected. No visual change for minimal erythematous dose was observed in all evaluations, for both groups. Chromatometer measures showed no difference in the mean of minimal erythematous dose at baseline between groups. Slight variation of color a after 10 weeks was observed [marginally significant (p = 0.054)], with a tendency to be greater for capsule use [marginally significant (p = 0.066)] and no adverse effects. Lycopene regular intake was safe and demonstrated no effect for systemic photoprotection against ultraviolet B; no correlation with serum lycopene was detected.

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Section: Discussionmentioning

confidence: 96%

Lycopene not in pill, nor in natura has photoprotective systemic effect

2015

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“…2,3 The authors explained that the reason for this restriction is because skin aging under the age of 55 years is caused predominantly by photoaging, rather than by photoaging and aging. All the subjects in the study were over 60 years.…”

Section: Unchanging Number Of Wrinklesmentioning

confidence: 99%

“…It is well-recognized that regular sunscreen use can help prevent photoaging of skin in fair-skinned people. [1][2][3] Therefore, application of sunscreen is recommended for the prevention of photoaging as well as squamous cell carcinoma (SCC) or actinic keratosis (AK) in many countries. In the USA, sunscreen is available over-the-counter.…”

Section: Introductionmentioning

confidence: 99%

The effects of continuous application of sunscreen on photoaged skin in Japanese elderly people—the relationship with the usage

Mizuno

Kunimoto

Seigan

et al. 2016

Journal of Dermatological Science

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“…In support of this, a study by Perez et al investigated the effect of over-or under-expression of a wide number of genes regulating antioxidant enzymes and found that only one had an effect on lifespan [51]. In addition, clinical data have failed to demonstrate a beneficial effect with a trial comparing regular sunscreen use with carotenoid supplementation, showing that beta-carotene had no overall effect on skin ageing [52]. A Cochrane review examining the effect of antioxidant supplementation on mortality found that supplementation with beta-carotene, vitamin E and vitamin A may increase mortality [53].…”

Section: Dietmentioning

confidence: 87%

Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin

Naidoo

Birch‐Machin

2017

Cosmetics

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Skin ageing is a complex process that is determined by both intrinsic and extrinsic factors, which leads to a progressive loss of structure and function. There is extensive evidence indicating that oxidative stress induced by reactive oxygen species plays an important role in the process of human skin ageing. Mitochondria are the major source of cellular oxidative stress and are widely implicated in cutaneous ageing. Extrinsic skin ageing is driven to a large extent by environmental factors and external stressors such as ultraviolet radiation (UVR), pollution and lifestyle factors which have been shown to stimulate the production of reactive oxygen species and generate oxidative stress. The oxidative damage from these exogenous sources can impair skin structure and function, leading to the phenotypic features of extrinsic skin ageing. The following review highlights the current evidence surrounding the role of mitochondria and oxidative stress in the ageing process and the influence of environmental factors such as ultraviolet radiation, pollution and diet on skin ageing.

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Sunscreen and Prevention of Skin Aging

Abstract: National Health and Medical Research Council of Australia.

Cited by 163 publications

References 39 publications

Lycopene not in pill, nor in natura has photoprotective systemic effect

Lycopene not in pill, nor in natura has photoprotective systemic effect

The effects of continuous application of sunscreen on photoaged skin in Japanese elderly people—the relationship with the usage

Oxidative Stress and Ageing: The Influence of Environmental Pollution, Sunlight and Diet on Skin

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