Sunlight, Vitamin D, and Osteomalacia in the Elderly

Hodkinson, H. M.; Round, Patrick; Stanton, Brielle; Morgan, C

doi:10.1016/s0140-6736(73)91362-7

Cited by 69 publications

(28 citation statements)

References 6 publications

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“…Hodkinson et al (11) found that exposure to sunlight assessed by questioning was correlated with serum calcium and phosphorus but not with alkaline phosphatase.…”

Section: Discussionmentioning

confidence: 99%

“…It has also been suggested (1) that osteomalacia in the elderly contributes much to the steep rise in incidence of femoral-neck fractures with advancing age. The main causes of osteomalacia in the elderly are a diet deficient in vitamin D (4,6,19) and lack of sunshine (4,11,19). Sometimes, osteomalacia is secondary to diseases of the alimentary tract which interfere with absorption (4).…”

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confidence: 99%

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Biochemical Parameters of Vitamin D Nutriture in Old People in Jerusalem

et al. 1979

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Serum 25-hydroxycholecalciferol (25[OH]D₃) levels and other parameters of vitamin D nutriture were examined in 58 subjects aged 70 or more, living in Jerusalem. They were compared with those of 54 young adults living in the same neighbourhood. No evidence was obtained of a lower level of vitamin D nutriture in the elderly compared to younger adults. Serum 25(OH)D₃ of the elderly adults was 18.4 (SEM: 1.4) ng/ml and in the younger adults, 17.8 (1.0) ng/ml. There was no seasonal variation in serum 25(OH)D₃, nor could a strong association be found between reported vitamin D intake nor with exposure to sunshine. There was a negative correlation between serum alkaline phosphatase and the calcium-phosphorus product in serum. High values of alkaline phosphatase were associated with reported low exposure to sunlight and, in elderly persons, with a reported low consumption of vitamin D.

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“…Hodkinson et al (11) found that exposure to sunlight assessed by questioning was correlated with serum calcium and phosphorus but not with alkaline phosphatase.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Biochemical Parameters of Vitamin D Nutriture in Old People in Jerusalem

et al. 1979

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“…(Hodkinson et at., 1973). Results 29 men and 33 women with ages ranging between 65 and 95 years were investigated.…”

Section: Methodsmentioning

confidence: 99%

“…A low vitamin D intake and limited sunlight exposure may be important causes. Tentative evidence for this is based on studies in which information on vitamin D status has been derived from measuring bone thickness or serum calcium, phosphate and alkaline phosphatase levels {MacLennan et al, 1972; Panel on Nutrition of the Elderly, \912, Hodkinson et al, 1973). Methods are now available for measuring the liver metabolites of cholecalciferol and ergocalciferol {Haddad and Chyu, 1971;Belsey et al, 1974;Edelstein et al, 1974).…”

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confidence: 99%

25-Hydroxy-Vitamin D, Diet and Sunlight Exposure in Patients Admitted to a Geriatric Unit

et al. 1978

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Dietary intake, sunlight exposure and 25-hydroxy-vitamin D levels were estimated in 62 patients admitted to a geriatric assessment unit. There was a significant correlation between vitamin D intake and 25-hydroxy-vitamin D levels but none between sunlight exposure and these. This suggests that in old age dietary deficiency may be a more important cause of metabolic bone disease than limited sunlight exposure.

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“…Sun Exposure, Activity, and Pain-A sun exposure score was determined using a sunlight exposure questionnaire (29,30). The questionnaire asked subjects about time spent outdoors during the previous week and amount of skin exposure.…”

Section: Clinical Assessmentsmentioning

confidence: 99%

Nutrient Status of Adults with Cystic Fibrosis

Gordon¹,

Anderson²,

Herlyn³

et al. 2007

Journal of the American Dietetic Association

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Nutrition is thought to influence disease status in patients with cystic fibrosis (CF). This crosssectional study sought to evaluate nutrient intake and anthropometric data from 64 adult outpatients with cystic fibrosis. Nutrient intake from food and supplements was compared with the Dietary Reference Intakes for 16 nutrients and outcomes influenced by nutritional status. Attention was given to vitamin D and calcium given potential skeletal implications due to cystic fibrosis. Measurements included weight, height, body composition, pulmonary function, and serum metabolic parameters. Participants were interviewed about dietary intake, supplement use, pulmonary function, sunlight exposure, and pain. The participants' mean body mass index (±standard deviation) was 21.8±4.9 and pulmonary function tests were normal. Seventy-eight percent used pancreatic enzyme replacement for malabsorption. Vitamin D deficiency [25-hydroxyvitamin D (25OHD)<37.5 nmol/L] was common: 25 (39%) were deficient despite adequate vitamin D intake. Lipid profiles were normal in the majority, even though total and saturated fat consumption represented 33.0% and 16.8% of energy intake, respectively. Reported protein intake represented 16.9% of total energy intake (range 10%-25%). For several nutrients, including vitamin D and calcium, intake from food and supplements in many participants exceeded recommended Tolerable Upper Intake Levels. Among adults with cystic fibrosis, vitamin D deficiency was common despite reported adequate intake, and lipid profiles were Copyright © 2007 Significant advances in the management of cystic fibrosis (CF) have increased the lifespan for patients with this common disease (1 in 3,900 white live births) (1). Previous research has suggested that patients with cystic fibrosis who have a good nutritional status have the best chance of maintaining and improving health (1-3). Nutritional therapy itself may also contribute to a better pulmonary status (4,5). A 1992 consensus report (1) emphasized the importance of detecting malnutrition in these patients to ensure optimal therapeutic management. A 2003 expert report on bone disease in cystic fibrosis cited both malnutrition and physical inactivity as risk factors for poor bone health (6).Osteoporosis is a common health problem as patients with cystic fibrosis survive longer (6-11), and one study of patients with this disease showed that decreased bone density was more prevalent in the most malnourished patients (8). A subnormal body mass index (BMI), among other factors, can compromise bone density (6,11,12). A high fracture risk and kyphosis are also documented in these patients (12). Serum vitamin D concentrations may be an important predictor of skeletal health, but the relationship between vitamin D status and bone density remains unclear in this disease (6,9-15).Most reports on nutrition in cystic fibrosis have been reviews, or include data collected in children (16)(17)(18)(19)(20)(21)(22)(23). In this study, anthropometric, nutritional, and lifestyle va...

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Sunlight, Vitamin D, and Osteomalacia in the Elderly

Cited by 69 publications

References 6 publications

Biochemical Parameters of Vitamin D Nutriture in Old People in Jerusalem

Biochemical Parameters of Vitamin D Nutriture in Old People in Jerusalem

25-Hydroxy-Vitamin D, Diet and Sunlight Exposure in Patients Admitted to a Geriatric Unit

Nutrient Status of Adults with Cystic Fibrosis

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