Sunlight in Vitamin D Deficiency: Clinical Implications

Sakamoto, Rosario Rose

doi:10.1016/j.nurpra.2019.01.014

Cited by 4 publications

(4 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The information regarding the exposure of sunlight was obtained by enquiring the child's parents whether they had a practice of exposing the infant to sunlight and also about how the child was dressed when exposed to the sun (Table 8). This was explained by Sakomoto RR (2019) 18 in his study which states that sunlight plays a very important role in mitigating the effects of vitamin D deficiency. We observed that the majority of the children who were diagnosed with respiratory tract infections and who had vitamin D deficiency were admitted in the intensive care unit when compared to IPD.…”

Section: Discussionmentioning

confidence: 96%

Vitamin D Deficiency and its Association with Respiratory Tract Infections in Pediatrics

Balaprabha

Hakeem

Sanjana

et al. 2022

Int J Life Sci Pharm Res

View full text Add to dashboard Cite

Respiratory tract infections (RTI) are a major cause of mortality and morbidity in children. Several studies have aim supplementation as a possible preventive measure against respiratory tract infections in children. Vitamin-D (sunshine vitamin) is a type of prohormone with various functions like extracellular calcium ion maintenance, immunomodulation in the body. The three major sources of Vitamin-D are Sun exposure, Diet and Supplements. The main objective of our study was to correlate the vitamin D deficiency in children with RTI’s. A prospective observational study was conducted for 6 months inpatient of the Pediatric department in tertiary care hospital. Demographic details, cause of admission, past medical and medication history, feeding history, sun exposure was taken by interviewing the guardian. Data of a total of 25 pediatric patients with various respiratory tract infection cases were collected, documented and their vitamin D levels were analyzed in our study. The vitamin D level of samples was analyzed by Electro chemiluminescence immunoassay. Statistical methods were applied and significant differences were observed among the vitamin D sufficient and deficient patients with RTI’s. It was observed that out of 25 cases, 16 cases had recurrent respiratory tract infections and 9 had non-recurrent respiratory tract infections which statistically shows P value < 0.05. This study significantly correlates vitamin D deficiency with respiratory tract infections in children. This study also suggests vitamin D as a supplement therapy as it plays an important role in the innate and the adaptive immunity.

show abstract

Section: Discussionmentioning

confidence: 96%

Vitamin D Deficiency and its Association with Respiratory Tract Infections in Pediatrics

Balaprabha

Hakeem

Sanjana

et al. 2022

Int J Life Sci Pharm Res

View full text Add to dashboard Cite

show abstract

“…Les différents éléments d'enquête épidémiologique ont été obtenus à l'aide d'un questionnaire, ce dernier a été réalisé à partir de l'étude du métabolisme de la vitamine D et d'une revue de la littérature mettant en avant les critères les plus susceptibles de discriminer les personnes carencées : âge 7 , sexe 8 , indice de masse corporelle (IMC) 9 , phototype¹ 0 , type de logement 9 , type de résidence (urbaine /rurale)¹¹, profession exercée (à l'extérieur ou à l'intérieur) 5 , pratique d'une activité physique 9 , exposition solaire , port de vêtements couvrants 5 , utilisation de crèmes solaires, consommation d'aliments enrichis en vitamine D 9 , connaissances sur la vitamine D 5 .…”

Section: Recueil Des Donnéesunclassified

“…Il est bien admis que les personnes ayant de faibles taux sériques de vitamine D ont généralement une pigmentation foncée de la peau¹º. Dans notre étude le teint foncé constituait un facteur de risque de la carence en vitamine D. L'exposition solaire est la principale source de vitamine D, elle dépend de la surface corporelle exposée, de la fréquence, la durée et le moment de la journée7 . Le temps d'exposition au soleil est le principal facteur déterminant du statut vitaminique D dans notre population.…”

unclassified

Epidemiology of hypovitaminosis D among apparently healthy young adults in Algeria

RAMDANE¹,

OUSSADOU²

2022

Rev Med Brux

View full text Add to dashboard Cite

Background: Hypovitaminosis D is a global public health problem. In Algeria, little work is done on the epidemiology of vitamin D deficiency targeting all at-risk populations. Objectives: The main objective of this study is to estimate the prevalence of hypovitaminosis D in healthy young adults. The secondary objectives are to identify the determinants of vitamin D status and to analyze the correlations between plasma calcidiol levels and other parameters of phosphocalcic metabolism. Material and methods: Cross-sectional descriptive, prospective and multicentric epidemiological survey of 945 subjects belonging to the Region of Blida (Algeria), assessment of 25-hydroxy-vitamin D, calcium, phosphorus, parathormone, alkaline phosphatase and albumin for each subject. The study also included a questionnaire to identify the determinants of vitamin D status in this population. Results: There is a high prevalence of hypovitaminosis D (calcidiol < 30 ng/ml), with 92.6% of subjects affected, of whom 27.5% had an insufficiency (calcidiol 20 -29 ng/ ml), however 65.1% of subjects were deficient (calcidiol < 20 ng/ml). No significant correlation was detected between 25-hydroxy-vitamin D and plasma calcium (R=0.051; P=0.115), a significant positive correlation was found between 25-hydroxy-vitamin D and phosphorus (R=0.146; P< 0,05). A negative correlation was detected between calcidiol and parathormone (R= -0.886; P< 0,05) and between calcidiol and alkaline phosphatase (R= -0.828; P< 0,05). Based on multivariate analysis, the 3 top risk factors that were associated with hypovitaminosis D are sun exposure time <30 min (adjusted OR =202.11, [95% CI]: 48.91; 835.10; P< 0,05), lack of knowledge about vitamin D (adjusted OR =46.45; [95% CI]: 20.84 ;103.52; P< 0,05), and dark phototype (adjusted OR =39.67; [95% CI]: 14.31; 109.99; P< 0,05). Conclusions: Hypovitaminosis D can be considered a public health problem in Algeria affecting young healthy populations. It is necessary to develop multisectorial programs in order to better address risk factors, particularly modifiable ones, and develop a strategy for prevention and care.

show abstract

“…Similarly, individuals with high levels of skin pigments, such as melanin, tend to have slower rates of vitamin D synthesis. [11][12][13] Melanin has photoprotective properties that can protect the body from ultraviolet radiation (UVR), so the amount of melanin is thought to affect the skin's ability to synthesise vitamin D. 14 However, the mechanism has not been fully understood. A study by Young et al on 102 volunteers with varying levels of Fitzpatrick skin type revealed a very small association between melanin and Vitamin D synthesis.…”

Section: Introductionmentioning

confidence: 99%

Association between melanin and vitamin D: A systematic review

Hartono

Sidharta

Astiarani

et al. 2023

JKKI

View full text Add to dashboard Cite

Globally, there is an increasing prevalence of vitamin D deficiency, including in Southeast Asia, which ranges from 6% to 70%. Vitamin D plays an important role in calcium metabolism and bone health. Melanin is one factor that contributes to vitamin D deficiency. It has photoprotective properties that inhibit vitamin D synthesis, but the mechanism has not been fully understood. To determine the mechanism of the association between melanin and vitamin D, this systematic review was conducted on 11 articles, including cross-sectional studies, cohort studies, and randomised controlled trials published from 2010 to 2020. The search included Pubmed, EBSCO, and Proquest databases, and data were synthesised from 11 studies. This critical review found nine of the 11 studies reported a significant association between melanin and vitamin D, while two reported non-significant results. Of the nine significant studies, eight reported that people with higher melanin have lower vitamin D levels, while one study suggested that melanin levels do not necessarily associate with lower vitamin D levels. In conclusion, the review establishes a significant association between melanin and vitamin D.

show abstract

Sunlight in Vitamin D Deficiency: Clinical Implications

Cited by 4 publications

References 49 publications

Vitamin D Deficiency and its Association with Respiratory Tract Infections in Pediatrics

Vitamin D Deficiency and its Association with Respiratory Tract Infections in Pediatrics

Epidemiology of hypovitaminosis D among apparently healthy young adults in Algeria

Association between melanin and vitamin D: A systematic review

Contact Info

Product

Resources

About