Sunlight and Vitamin D Linking Bones to Blood Vessels Via Mirroring Through Calcium Transit

Abstract

Sunlight induces vitamin D (VitD) synthesis and strengthens bones via nitric oxide (NO), simultaneously it cleans blood vessels (improving endothelial function) and this is supported by calcium transit within the human systems. During winters (low ultraviolet index season) and even in summers (polar locations) humans lack adequate sunlight exposure thus mirroring osteoporosis (T score <2.5) and hypertension (SBP>140mm of Hg / DBP>90 mm of Hg) in general population. VitD is a hormone from the biochemical point of view because it is mostly synthesized in the skin under the direct action of natural UVR B. 7-dehydrocholestrol undergoes conversion in to Previtamin D which undergoes thermal isomerization within hours to form cholecalciferol. The hydroxylation in