Sun Protective Potential and Physical Stability of Herbal Sunscreen Developed from Afghan Medicinal Plants

Ahmady, Amina; Amini, Mohammad Humayoon; Zhakfar, Aqa Mohammad; Babak, Gulalai; Sediqi, Mohammad Nasim

doi:10.4274/tjps.galenos.2019.15428

Cited by 21 publications

(12 citation statements)

References 22 publications

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“…The pH of a topical formulation should ideally be slightly acidic in the range of 5 to 5.5, especially in the case of topical formulations that are used often. In actuality, topical preparations are appropriate in the pH range of 5-7 [27,33]. Extrudability of herbal sunscreens was assessed because high consistency formulations may not extrude from tubes, whilst low viscous formulations may flow fast, necessitating the use of an appropriate consistency to extrude gel from tubes.…”

Section: Resultsmentioning

confidence: 99%

Formulation and Evaluation of Herbal Sunscreens: An Assessment Towards Skin Protection from Ultraviolet Radiation

Tiwari¹,

Indu²,

Gupta³

et al. 2022

Pharmacophore

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Sunscreen lotion is a sort of product that protects against the sun's harmful rays by containing ultraviolet radiation (UV rays), which is divided into two types: ultraviolet radiation A (UVA) and ultraviolet radiation B (UVB). The incorporation of herbal materials into sunscreen is one of the most effective and natural ways to protect against the sun, as measured by the sun protection factor (SPF), as well as the detrimental side effects of toxic chemicals. The present study aimed to develop herbal sunscreens containing turmeric (strong antiseptic property which protects skin from bacteria caused by excess sweat), coconut oil (used as a sun-block agent and helps to protect skin from sun damage), aloe vera (give a cooling effect to the skin and work as skin barrier), lemon (used to protect skin for sunburn) which will be effective for skin and protect skin against harmful sun rays, sunburn, and skin cancer. Prepared herbal sunscreens were evaluated for physicochemical characteristics, SPF, thermal stability, antioxidant activity, in vitro mutagenicity, and stability. Results showed that the F5 and F6 herbal sunscreens were of good consistency and viscosity with excellent antioxidant, non-mutagenic, nonirritant, stability activity and possessed 33.50 SPF for normal skin. In comparison to F1 through F4, formulations with a coconut oil base and carrot seed extract (F5 and F6) were shown to be stable and effective, with a high SPF.

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Section: Resultsmentioning

confidence: 99%

Formulation and Evaluation of Herbal Sunscreens: An Assessment Towards Skin Protection from Ultraviolet Radiation

Tiwari¹,

Indu²,

Gupta³

et al. 2022

Pharmacophore

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“…Nowadays, sunscreen products become more popular on markets because people need protection against ultraviolet (UV) radiation [1]. The market of sunscreen products amounts to 13,5 billion USD in 2020 and is projected to become 20,1 billion USD in 2027, growing by 5,8% per year [2a].…”

Section: Introductionmentioning

confidence: 99%

“…The market of sunscreen products amounts to 13,5 billion USD in 2020 and is projected to become 20,1 billion USD in 2027, growing by 5,8% per year [2a]. The huge amount of sunscreen products is because UV radiation can cause skin damage, such as sunburns, wrinkles, lower immunity against infections, premature aging, and cancer [1]. The main mechanism of skin damage by UV radiation is the formation of reactive oxygen species (ROS) that interact with proteins and lipids.…”

Section: Introductionmentioning

confidence: 99%

Physical Characteristics and UV Protection (In Vitro) of Gambier Leaf Extract Lotion

Winarti

Innawati

Hemani

2022

IOP Conf. Ser.: Earth Environ. Sci.

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Nowadays, sun care products become one of the most developed market amounts of 13.5 billion USD in 2020 and projected to become 20.1 billion USD in 2027, growing by 5.8% per year. The need for sun care products derived from natural ingredients is also increasing as people worry about the side effect of synthetic material. Gambier leaf contains a lot of polyphenol compounds such as catechin that have antioxidant properties. Antioxidant is useful as a defense system against free radicals and ultraviolet radiation. The Objective of the research was to find out the physical characteristics (stability, color, pH, viscosity) and the Sun Protection Factor (SPF) score of sunscreen lotions containing extract gambier leaf. Gambier leaf extract was formulated into lotions with different concentrations: 0% (control); 0,25%; 0,5%; and 1% with three replicates. The ability of the lotion with gambier leaf extract as sunscreen was measured by determining SPF (Sun Protection Factor) score in vitro using a UV-vis spectrophotometer. The result showed that lotion with 0%; 0.25%; 0.5%; and 1.0% concentration has good physical stability during storage. Lotion’s SPF scoring showed that the SPF score in the lotion was increasing along with the addition of gambier leaf extract on each concentration. The SPF score for the concentration 0.25%; 0.5%; and 1.0%. were as follows: 7.01; 12.45; dan 26.55; and pH was about 5.55 – 6.93. Gambier extract with a concentration of 1.0% can be applied for the formulation of SPF lotion

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“…Ahmady et al studied the phytochemical profile and sun protection potentials of the crude and purified extracts. Elaeagnus angustifolia pure extract (EAPE), sesame oil, and sea buckthorn oil were the herbal materials chosen for the sunscreen formulation based on their findings (Ahmady et al, 2020). Netto and Jose focused on developing sunscreen which contained silymarin, a flavonoid that has strong antioxidant effects, in solid lipid nanoparticles, a new type of drug carrier that improves medication stability while simultaneously increasing penetration (Netto and Jose 2018).…”

Section: Introductionmentioning

confidence: 99%

Development of Sunscreen Containing Alpha-Mangostin Riched Extract with Anti-Tyrosinase Activities

Tangyuenyongwatana¹,

Gritsanapan²

2022

CMUJNS

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This study focused on the development of extracts from mangosteen rinds for use as whitening and sunscreen agents. Mangosteen rinds were obtained from 9 locations in the East and the South of Thailand. Ethanol (95%) crude rind extracts were prepared and separated by column chromatography. The fractions were collected from top (F1-F4) and mid spots (F12-F15). These fractions were subjected to tyrosinase inhibitory activity assay and found that the top spot exhibited low activity with IC50 > 100 µg/mL while the mid spots inhibited tyrosinase enzyme at IC50 18.48 µg/mL which is more sensitive than a positive control, kojic acid (38.46 µg/mL). The mid spots fraction from the crude extract of Chanthaburi sample 1 was analyzed with HPLC and was assigned as MGS-1 extract which contained a high amount of α-mangostin. MGS-1 extract was formulated as oil in water cream with 2, 4, 6, and 9 %w/w extract. All creams were subjected to measure SPF and UVA/UVB ratio using an Optometrics SPF-290S analyzer. It was found that the cream with 6 %w/w MGS-1 extract showed the best results with SPF at 10.36 ± 1.07 and had a UVA/UVB ratio equal to 0.451. These sunscreen properties are close to the properties of Salisol-3 (benzophenone), a standard sunscreen. In conclusion, MGS-1 extract has a good potential to be used as a whitening and sunscreen agent in cosmetics with a lower cost of substrate because mangosteen rinds can be found as waste from eating mangosteen fruit every year in Thailand. Keywords: Mangosteen rind, MGS-1 extract, Tyrosinase inhibition, Whitening agent, Sunscreen

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Sun Protective Potential and Physical Stability of Herbal Sunscreen Developed from Afghan Medicinal Plants

Cited by 21 publications

References 22 publications

Formulation and Evaluation of Herbal Sunscreens: An Assessment Towards Skin Protection from Ultraviolet Radiation

Formulation and Evaluation of Herbal Sunscreens: An Assessment Towards Skin Protection from Ultraviolet Radiation

Physical Characteristics and UV Protection (In Vitro) of Gambier Leaf Extract Lotion

Development of Sunscreen Containing Alpha-Mangostin Riched Extract with Anti-Tyrosinase Activities

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