Summer tuberculosis

Kelsey, M.C.; Mitchell, Colin; Griffin, Marsha; Emmerson, A.M.

doi:10.1136/thx.54.9.861b

Cited by 4 publications

(5 citation statements)

References 2 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among them, a low vitamin D level was evidenced as a potential factor related to impaired host immune resistance accompanying with ‘reactivation’ of M. tuberculosis during the incubation [ 31 ]. And vitamin D deficiency in winter has been shown to correlate with the peak of TB notifications in summer in Hong Kong [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

“…The effects of lower average temperature on TB cases occurred at lagged 2 months in Southwest China [7], at a lag of 2 quarters in Vietnam [27], and at lags of 1-6 quarters in tuberculosis during the incubation [31]. And vitamin D deficiency in winter has been shown to correlate with the peak of TB notifications in summer in Hong Kong [32].…”

Section: The Exposure-response-lag Relationship Between Tb Notificatimentioning

confidence: 95%

See 1 more Smart Citation

Temperature and humidity associated with increases in tuberculosis notifications: a time-series study in Hong Kong

Xu¹,

Liu

et al. 2020

Epidemiol. Infect.

View full text Add to dashboard Cite

Previous studies have revealed associations of meteorological factors with tuberculosis (TB) cases. However, few studies have examined their lag effects on TB cases. This study was aimed to analyse nonlinear lag effects of meteorological factors on the number of TB notifications in Hong Kong. Using a 22-year consecutive surveillance data in Hong Kong, we examined the association of monthly average temperature and relative humidity with temporal dynamics of the monthly number of TB notifications using a distributed lag nonlinear models combined with a Poisson regression. The relative risks (RRs) of TB notifications were >1.15 as monthly average temperatures were between 16.3 and 17.3 °C at lagged 13–15 months, reaching the peak risk of 1.18 (95% confidence interval (CI) 1.02–1.35) when it was 16.8 °C at lagged 14 months. The RRs of TB notifications were >1.05 as relative humidities of 60.0–63.6% at lagged 9–11 months expanded to 68.0–71.0% at lagged 12–17 months, reaching the highest risk of 1.06 (95% CI 1.01–1.11) when it was 69.0% at lagged 13 months. The nonlinear and delayed effects of average temperature and relative humidity on TB epidemic were identified, which may provide a practical reference for improving the TB warning system.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: The Exposure-response-lag Relationship Between Tb Notificatimentioning

confidence: 95%

Temperature and humidity associated with increases in tuberculosis notifications: a time-series study in Hong Kong

Xu¹,

Liu

et al. 2020

Epidemiol. Infect.

View full text Add to dashboard Cite

show abstract

“…The hormonally active form has, in addition to its calciotropic effect, a critical regulatory role in immune functions. Seasonality of TB with winter troughs and summer peaks has been reported from the UK and Hong Kong, which is reversely associated with vitamin D seasonal variation [3,4,17]. To explain ''summer TB'', a possible delayed effect of vitamin D deficiency on progression to TB must be postulated.…”

Section: Discussionmentioning

confidence: 99%

“…The lower vitamin D levels found in TB patients may be less related to diet or skin pigmentation, but rather to an abnormal handling of the vitamin [18]. Thus, the actual role of vitamin D in protection against TB remains elusive despite many speculations to the contrary [17,19]. Nutrition is influenced by season and may assert its effect on immune response in more complex ways that defy the singling out of one isolated factor [20].…”

Section: Discussionmentioning

confidence: 99%

Seasonality of tuberculosis in an Eastern-Asian country with an extreme continental climate

Naranbat

Nymadawa²,

Schopfer³

et al. 2009

European Respiratory Journal

View full text Add to dashboard Cite

Aggregate monthly notifications of incident sputum smear-positive tuberculosis (TB) in Mongolia, stratified by sex and age groups, were analysed separately for Ulaanbaatar, Mongolia, and the rest of the country for the 9-yr period from 1998 to 2006. TB notifications were compared with ambient surface temperature.More than twice as many TB cases were notified in the peak month (April) compared with the trough months (October-December), paralleling the temperature curve. The fluctuations recurred consistently over the entire observation period, were identical in the capital compared with the rest of the country, and were independent of age and sex.TB notifications parallel the temperature amplitudes and have a magnitude not reported elsewhere. We hypothesise that the influence of temperature on life either indoors or outdoors is consistent with the transmission probability of Mycobacterium tuberculosis and the subsequent delay to disease recognition and notification with the incubation period, possibly co-determined by other factors, rather than accessibility to services.

show abstract

“…In 1996, Douglas reported an unique seasonal pattern (summer peak) of tuberculosis compared with most other respiratory diseases [3]. Since then, there were many other researchers recognized various patterns of seasonality of TB [4][5][6][7][8][9][10][11][12][13][14][15], except for a few studies in which no obvious pattern of seasonality of TB was found [16]. Some studies showed that there was a single springearly summer peak [4][5][6][7][8], while other studies found a single summer peak [3,9,10].…”

Section: Introductionmentioning

confidence: 99%

Seasonal Variation of Newly Notified Pulmonary Tuberculosis Cases from 2004 to 2013 in Wuhan, China

et al. 2014

View full text Add to dashboard Cite

BackgroundAlthough there was a report about the seasonal variation in Wuhan city, it only analyzed the prevalence data of pulmonary tuberculosis (TB) cases, and just studied the seasonality by subgroup of smear positive and negative from 2006 to 2010 by spectral analysis. In this study, we investigated the seasonality of the total newly notified pulmonary TB cases by subgroups such as time period, sex, age, occupation, district, and sputum smear result from 2004 to 2013 in Wuhan by a popular seasonal adjustment model (TRAMO-SEATS).MethodsMonthly pulmonary TB cases from 2004 to 2013 in Wuhan were analyzed by the TRAMO-SEATS seasonal adjustment program. Seasonal amplitude was calculated and compared within the subgroups.ResultsFrom 2004 to 2013, there were 77.76 thousand newly notified pulmonary TB cases in Wuhan, China. There was a dominant peak spring peak (March) with seasonal amplitude of 56.81% and a second summer peak (September) of 43.40%, compared with the trough month (December). The spring seasonal amplitude in 2004–2008 was higher than that of 2009–2013(P<0.05). There were no statistical differences for spring seasonal amplitude within subgroups of gender, age, district, and sputum smear result (P>0.05). However, there were significant differences in spring seasonal amplitude by occupation, with amplitude ranging from 59.37% to 113.22% (P<0.05). The summer seasonal amplitude in 2004–2008 was higher than that of 2009–2013(P<0.05). There were no statistical differences in summer seasonal amplitude within subgroups of gender, district, sputum smear result(P>0.05). There were significant differences in summer seasonal amplitude by age, with amplitude ranging from 36.05% to 100.09% (P<0.05). Also, there were significant differences in summer seasonal amplitude by occupation, with amplitude ranging from 43.40% to 109.88% (P<0.05).ConclusionsThere was an apparent seasonal variation in pulmonary TB cases in Wuhan. We speculated that spring peak in our study was most likely caused by the increased reactivation of the latent TB due to vitamin D deficiency and high PM2.5 concentration, while the summer peak was mainly resulted from the enhanced winter transmission due to indoor crowding in winter, overcrowding of public transportation over the period of the Spring Festival and health care seeking delay in winter.

show abstract

Summer tuberculosis

Cited by 4 publications

References 2 publications

Temperature and humidity associated with increases in tuberculosis notifications: a time-series study in Hong Kong

Temperature and humidity associated with increases in tuberculosis notifications: a time-series study in Hong Kong

Seasonality of tuberculosis in an Eastern-Asian country with an extreme continental climate

Seasonal Variation of Newly Notified Pulmonary Tuberculosis Cases from 2004 to 2013 in Wuhan, China

Contact Info

Product

Resources

About