Sulfonimide-Based Dendrimers: Progress in Synthesis, Characterization, and Potential Applications

Abstract

There are more than 50 families of dendrimers, and some of which, such as polyamidoamine PAMAM, are well studied, and some are just starting to attract the attention of researchers. One promising type of dendrimers is sulfonimide-based dendrimers (SBDs). To date, SBDs are used in organic synthesis as starting reagents for the convergent synthesis of higher generations dendrimers, in materials science as alternative electrolyte solutions for fuel cells, and in medicinal chemistry as potential substances for drug transfer procedures. Despite the fact that most dendrimers are amorphous substances among the SBDs, several structures are distinguished that are prone to the formation of crystalline solids with melting points in the range of 120–250 °C. Similar to those of other dendrimers, the chemical and physical properties of SBDs depend on their outer shell, which is formed by functional groups. To date, SBDs decorated with end groups such as naphthyl, nitro, methyl, and methoxy have been successfully synthesized, and each of these groups gives the dendrimers specific properties. Analysis of the structure of SBD, their synthesis methods, and applications currently available in the literature reveals that these dendrimers have not yet been fully explored.

Progress in the Enantioselective Synthesis of Sulfur (VI) Compounds

“…[16][17] Finally, Nicosulfuron is a selective herbicide used post-emergence to protect corn crops from weeds. [18][19] Recent attention has been directed towards enantioenriched sulfonimidate esters (V) [20][21][22] and enantioenriched sulfonimidoyl halides (VI), [23] which have become focal points in the synthesis of a diverse array of pharmacophores for the development of novel drugs in conjunction with various molecular entities.…”

Efficient and environmentally-friendly access to 4,5-unsaturated sulfonamides through ligand-free copper-BF3-catalyzed three-component alkene carbo-sulfonamidation

“…15,16 Alkenes have been extensively used as starting materials to construct various useful compounds. [17][18][19][20] As a result, various two-or three-component addition reactions of alkenes have been developed and provided a range of functionalized products. [21][22][23][24][25][26] Two-component reactions of alkenes, namely hydro-heteroatom addition reactions, are more common than three-component carbo-heteroatom reactions.…”

Universal Mass Production of Biomass-Derived Nanosized Porous Carbon Spheres as a Superior Nonmetal Catalyst for Aerobic Oxidation of Hydrocarbons

“…NPCSs were facilely obtained after static-air calcinations of NCSs. Considering the regular high-density surface functionality of dendrimers and the cocatalytic oxidation activity of quaternary ammonium compounds, − the polyamidamine dendrimer (PD)-based quaternization and amidation functionalization were designed to covalently anchor abundant NHPI onto NPCSs. These NHPI-anchored NPCSs (NHPI-NPCSs) were applied in the catalytic oxidation of diverse hydrocarbons.…”