Sulfonamides in the environment: a review and a case report

Hruška, K.; Fránek, Milan

doi:10.17221/4969-vetmed

Cited by 99 publications

(48 citation statements)

References 89 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The review follows the format of our recently published reviews (Eyer and Hruska 2012;Hruska and Franek 2012). Selected papers are presented in tables with the basic key words in the first column, full or shortened abstract in the second column and the link to the List of References in the third column.…”

Section: The Format Usedmentioning

confidence: 99%

Mycobacteria in water, soil, plants and air: a review

Hruška¹,

Kaevska²

2012

Vet. Med.

Self Cite

View full text Add to dashboard Cite

Amazingly, despite the 24 143 papers on mycobacteria, indexed in the Web of Science database during the last six years, published by 67 008 authors from 13 128 organizations located in 166 countries or territories, internationally accepted legal directives on how to control the public health risk associated with environmental mycobacteria have yet to be developed. Mycobacteria are human and animal pathogens, causing not only tuberculosis and leprosy, but mycobacterioses of skin, soft tissues and lung. Due to their cell wall composition and their adaptability mycobacteria can survive in different habitats for years. Their immunomodulatory ability has been recognised for more than 50 years and hundreds of papers published during the last two decades have demonstrated that small chemical products derived from mycobacterial cells participate in inflammatory pathways involved the pathogenesis of important human diseases like Crohn's disease, asthma, type 1 diabetes mellitus, psoriasis, arthrosis, Blau syndrom, sarcoidosis, autism etc. Mycobacteria can influence inflammatory pathways not only as live organisms, but also by means of components derived from dead cells. Pasteurisation or cooking does not affect this ability. Hence, how many mycobacterial cells are ingested, what factors play a role concurrently, and how long the harmful effect persists become important questions. This paper presents only a short review based on selected papers about mycobacteria in water, soil, plants and air with the aim of attracting attention to this significant global problem and of making the first steps towards protection of people. Selected bibliographic references of published data from 2007 to 2012 are presented in easy-to-navigate tables.Keywords: Mycobacterium; water; soil; plant; vegetables; air; biofilm; sediment; determination; zoonoses; food safety List of abbreviations CFU = colony forming units; DGGE = denaturation gradient gel electrophoresis; IMS = immuno-magnetic separation; IS = insertion sequence; ITS = intergenic transcribed spacer; MAC = Mycobacterium avium complex; MAP/Map = Mycobacterium avium subsp. paratuberculosis; MTC = Mycobacterium tuberculosis complex; MWF = metal working fluids; nPCR = nested PCR; NTM = non-tuberculous mycobacteria; PCR = polymerase chain reaction; PPM = potentially pathogenic mycobacteria; qPCR = quantitative real time PCR; RFLP = restriction fragment length polymorphism

show abstract

Section: The Format Usedmentioning

confidence: 99%

Mycobacteria in water, soil, plants and air: a review

Hruška¹,

Kaevska²

2012

Vet. Med.

Self Cite

View full text Add to dashboard Cite

show abstract

“…The synthetic compound sulfamethoxazole (SMX) is one of the most popularly prescribed and consumed sulfonamide antibiotics (Cavallucci 2007;Hruska and Franek 2012) leading to its presence in the aquatic environment via WW discharge (Avisar et al 2009;Santos et al 2010) and its frequent detection in WWs at up to microgram-per-liter levels and surface waters at nanogram-per-liter levels (Batt et al 2007;Joss et al 2005;Kolpin et al 2002;Miège et al 2009;Peng et al 2006;Yargeau et al 2007;Gao et al 2012a). At these concentrations, SMX has been found to be mutagenic but not acutely toxic to Vibrio fisheri and Daphnia magna (Isidori et al 2005) and to be phytotoxic to algae (García-Galán et al 2011) and other plant species (Hillis et al 2011).…”

Section: Smx Usage and Presence In The Environmentmentioning

confidence: 99%

Biodegradation of sulfamethoxazole: current knowledge and perspectives

Larcher

Yargeau

2012

Appl Microbiol Biotechnol

119

View full text Add to dashboard Cite

Antibiotic compounds, like sulfamethoxazole (SMX), have become a concern in the aquatic environment due to the potential development of antibacterial resistances. Due to extensive consumption, excretion and disposal, SMX has been frequently detected in wastewaters and surface waters. This has led to numerous studies investigating the nature of SMX, with many researchers focusing on the biodegradation and persistence of SMX during wastewater treatment and in the environment. This review provides a summary of recent developments, outlines the discrepancies in observations and results, and demonstrates the need for further research to determine optimal biological removal strategies for SMX and other antibiotics.

show abstract

“…Such compound has been found in aquatic media owing to the inefficient elimination during sewage treatment and has been shown to significantly absorb solar light [15][16][17]. Some studies were devoted to the elimination of sulfamethoxazole using various photocatalytic systems [18] and permit its entire elimination.…”

Section: Introductionmentioning

confidence: 99%

Photochemical Degradation of the Antimicrobial Sulfamethoxazole upon Solar Light Excitation: Kinetics and Elucidation of Byproducts Using LC/ ESI+/MS2 Technique

Mezghich¹,

Ayari²,

Sarakha³

2017

Mass Spectrom Purif Tech

View full text Add to dashboard Cite

The fate of the antimicrobial compounds in the environment is of great interest since their presence in the aquatic systems has raised environmental problems. More and more chemicals of this class are treated as emerging contaminants. The degradation of these compounds may result in the formation of a wide array of metabolites which can be more toxic than the parent substrate. Therefore, precise elucidation of all possible transformation products as well as a thorough study of their physico-chemical and biological properties is of great importance. The present work deals with the study of the photochemical behavior of sulfamethoxazole from the kinetic aspect as well as the elucidation of the products arising from the solar irradiation of the antimicrobial sulfamethoxazole in the aqueous solutions. HPLC/MS and HPLC/MS/MS with accurate mass measurements were used for this purpose. stainless steel equipped with two germicidal lamps (Mazda T815 15W) emitting selectively at 254 nm and symmetrically installed around the cylinder were used. The reactor, a quartz tube (d=2.5 cm) containing a maximum of 50 mL solution, was located in the centre of the container.The disappearance of the antimicrobial and the formation of the products were followed by high performance liquid chromatography using a Waters 2695 HPLC (Alliance) chromatograph system equipped with a Waters 2998 photodiode array detector. The experiments were performed by UV detection at either 250 nm or 280 nm and by using a reverse phase Nucleodur column (Macherey-Nagel, 100-5 C18 ec; 150-4.6 mm). The flow rate was 1.0 mL min -1 and the injected volume was 50 µL. The elution was accomplished with water, formic acid (0.1%) and acetonitrile (60/40 v/v). A Waters/Micromass LC/QTOF tandem mass spectrometer (Micromass, Manchester, UK), with an orthogonal geometry Z-spray ion source, was used for LC/ESI/MS and LC/ESI/MS/MS experiments. LC separation was performed using the gradient program reported in the literature [19]. Eluate was subjected to electrospray ionization (ESI) in the positive ion as well as negative mode and resulted in the formation of protonated molecules and deprotonation of the sample components. Scanning was performed in the range between m/z 60 and 600. The elemental composition of the recorded ions was further determined using MassLynx Elemental Composition software V4.1 (Micromass). C, H, N, O and S were selected as possible elements present. In LC/MS analyses, in order to assign the elemental formulas, the minimum and maximum atoms of each element were set as follows: C from 1 to 20; H from 1 to 20; N from 0 to 5; O from 0 to 10 and S from 0 to 2. No nitrogen rule, ring and double bond equivalents were applied. The maximum deviation was set to 10 ppm. Five scans were combined before the integration of the

show abstract

Sulfonamides in the environment: a review and a case report

Cited by 99 publications

References 89 publications

Mycobacteria in water, soil, plants and air: a review

Mycobacteria in water, soil, plants and air: a review

Biodegradation of sulfamethoxazole: current knowledge and perspectives

Photochemical Degradation of the Antimicrobial Sulfamethoxazole upon Solar Light Excitation: Kinetics and Elucidation of Byproducts Using LC/ ESI+/MS2 Technique

Contact Info

Product

Resources

About