Sulfide causes histological damage, oxidative stress, metabolic disorders and gut microbiota dysbiosis in juvenile sea cucumber Apostichopus japonicus Selenka

Biogenic Selenium Nanoparticles Synthesized with Alginate Oligosaccharides Alleviate Heat Stress-Induced Oxidative Damage to Organs in Broilers through Activating Nrf2-Mediated Anti-Oxidation and Anti-Ferroptosis Pathways

“…Basal diet and nutrient composition are presented in Table 1. 3 Measured value 1 Premix provided per kilogram of diet: 9000 IU of vitamin A, 3240 IU of vitamin D3, 6 IU of vitamin E, 30.75 mg of vitamin K, 1.5 mg of vitamin B1, 4.5 mg of vitamin B2, 1.5 mg of vitamin B6, 10 µg of vitamin B12, 9 mg of niacin, 0.45 mg of folic acid, 1000 mg of choline, and 9 mg of pantothenic acid. 2 Premix provided per kilogram of diet: 40 mg of Zn, 60 mg of Mn, 80 mg of Fe, 8 mg of Cu, 0.35 mg of I, 0.15 mg of Se.…”

“…2 Premix provided per kilogram of diet: 40 mg of Zn, 60 mg of Mn, 80 mg of Fe, 8 mg of Cu, 0.35 mg of I, 0.15 mg of Se. 3 Se was the mean value of three repeated tests of experimental diet samples. The content of Se in the experimental diet of the control group was 0.282 mg/kg, and that of the SeNPs-AOS group was 0.696 mg/kg.…”

“…With the rise of global temperature and high-density feeding, heat stress (HS) has become the primary environmental stressor in broiler production, which has deleterious impacts on broiler productivity and health [1]. It is already clear that HS results in reduced feed intake, growth restriction, and metabolic disorders in broilers [2,3]. Meanwhile, multiple studies have found that HS-induced oxidative stress in organs, leading to organ injury and dysfunction, which is also an important reason for HS causing production losses in broilers [4][5][6].…”