Sulfidation of silver nanoparticle reduces its toxicity in zebrafish

Devi, G. Prathinkra; Ahmed, Khawaja Ashfaque; Varsha, M.K.N. Sai; Shrijha, B.S.; Lal, Kewal; Veerappan, Anbazhagan; Raman, Thiagarajan

doi:10.1016/j.aquatox.2014.11.007

Cited by 118 publications

(58 citation statements)

References 43 publications

(37 reference statements)

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“…Afterward, Suresh et al assessed the toxicity of biogenic Ag 2 S nanoparticles on Gram-negative (Escherichia coli and Shewanella oneidensis) and Gram-positive (Bacillus subtilis) bacterial systems, as well as eukaryotic cell lines including mouse lung epithelial (C10) and macrophage (RAW-264.7) cells, and proved that the nanoparticles were neither inhibitory nor cytotoxic to any of these organisms [13]. Same results were also reported by Devi et al that the sulfidation of AgNPs reduced biological toxicity of silver nanoparticles in adult vertebrates [65]. Silver sulfide has also been implemented in various nanoscale optical, atomic switching and electronic applications including IR detectors, fuel cells, random access memory (RAM) devices, cross bar electronic circuits, H 2 S sensing, photoconductors, photovoltaic cells, resistive switching and solar selective coatings.…”

Section: Silver Sulfide Nanoparticlessupporting

confidence: 80%

Recent achievements in the microbial synthesis of semiconductor metal sulfide nanoparticles

Hosseini

Sarvi

2015

Materials Science in Semiconductor Processing

102

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Section: Silver Sulfide Nanoparticlessupporting

confidence: 80%

Recent achievements in the microbial synthesis of semiconductor metal sulfide nanoparticles

Hosseini

Sarvi

2015

Materials Science in Semiconductor Processing

102

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“…In view of the toxicity profile of AgNP, some recent studies proposed that the chemical transformations of Ag nanoparticles can be an important way to slow down the nanoparticle toxicity. For instance, Devi et al [108] proved that sulfidation method can delay AgNP toxicity in zebrafish model. Furthermore, biosynthesis of silver nanoparticles can also be a better way to reduce its toxicity level [109].…”

Section: Nanotoxicology In Zebrafishmentioning

confidence: 99%

Zebrafish: A complete animal model to enumerate the nanoparticle toxicity

et al. 2016

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Presently, nanotechnology is a multi-trillion dollar business sector that covers a wide range of industries, such as medicine, electronics and chemistry. In the current era, the commercial transition of nanotechnology from research level to industrial level is stimulating the world’s total economic growth. However, commercialization of nanoparticles might offer possible risks once they are liberated in the environment. In recent years, the use of zebrafish (Danio rerio) as an established animal model system for nanoparticle toxicity assay is growing exponentially. In the current in-depth review, we discuss the recent research approaches employing adult zebrafish and their embryos for nanoparticle toxicity assessment. Different types of parameters are being discussed here which are used to evaluate nanoparticle toxicity such as hatching achievement rate, developmental malformation of organs, damage in gill and skin, abnormal behavior (movement impairment), immunotoxicity, genotoxicity or gene expression, neurotoxicity, endocrine system disruption, reproduction toxicity and finally mortality. Furthermore, we have also highlighted the toxic effect of different nanoparticles such as silver nanoparticle, gold nanoparticle, and metal oxide nanoparticles (TiO2, Al2O3, CuO, NiO and ZnO). At the end, future directions of zebrafish model and relevant assays to study nanoparticle toxicity have also been argued.

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“…When it reaches the aquatic environment, AgNPs most likely to enter the ecosystems produce a physiological response and genotoxicity in animals (Luoma et al 2008;Sohn et al 2015). Further studies also revealed Ag-NPs cause the oxidative stress in the aquatic organisms (Devi et al 2015;Khan et al 2016). They increase the production of reactive oxygen species (ROS) and causes lipid peroxidation, intact with nucleic acid, lipid, protein, causes loss of membrane integrity, functional changes and mutation.…”

Section: Introductionmentioning

confidence: 99%

Assessment of toxicity in fresh water fish Labeo rohita treated with silver nanoparticles

2017

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Silver nanoparticles (17.78 ± 12.12 nm) were synthesized by the reduction of 0.5 M silver nitrate using formaldehyde as reducing and triethylamine as promoting and stabilizing agent. The particles were grain like agglomerates with spherical, centered-face cubic and crystalline in nature. The sample was highly pure with amine (NH) as associated and capping molecules. Further, the genotoxicity and oxidative stress of these particles were evaluated using Labeo rohita (L. rohita) as genetic model exposed (10-55 mg L -1 dose) through aquatic medium for 28 days. The cells were produced with micronuclei, fragmented, lobed and buds nuclei in dose dependent manner. The highest incidence of comet was recoded (27.34 ± 5.68) at 55 mg L -1 Ag-NPs and 14 days treatment. Then frequency was decreased to 22.65 ± 6.66% after 28 days due to complex repair mechanism. Moreover, the treatment also produces the oxidative stress and disturbs the level of GST in gill and liver tissue. There was a sharp decline in the activities of GST and this decrease of activity increase the MDA content. Further, the elevated level of GSH represents that the liver has started defensive mechanism against oxyraidcals. This study concluded, Ag-NPs are genotoxic in nature and produce micronuclei, comet cells and also induces oxidative stress in aquatic organisms.

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Sulfidation of silver nanoparticle reduces its toxicity in zebrafish

Cited by 118 publications

References 43 publications

Recent achievements in the microbial synthesis of semiconductor metal sulfide nanoparticles

Recent achievements in the microbial synthesis of semiconductor metal sulfide nanoparticles

Zebrafish: A complete animal model to enumerate the nanoparticle toxicity

Assessment of toxicity in fresh water fish Labeo rohita treated with silver nanoparticles

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