Sulfated surfaces in sensitivity: An ‘on-off’ switch for anaphylaxis?

Lasser, Elliott C.

doi:10.1016/0306-9877(91)90058-7

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Sulphate1

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2009

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Cited by 3 publications

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“…Sulphates may also form conjugates with polysaccharides and proteoglycans on cell surfaces. These have been postulated to form the trigger for anaphylaxis [90]. Sulphates may accumulate up to 10-fold during renal failure and may cause a metabolic acidosis with an increased anion gap that responds readily to haemodialysis [91].…”

Section: Sulphatementioning

confidence: 99%

Anions and the anaesthetist

2002

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SummaryAnions are the negative components of most chemical structures and play many important physiological and pharmacological roles that are of interest to the anaesthetist. Their relevance is reviewed with a particular emphasis on the inorganic anions (halides, bicarbonate, phosphate and sulphate) and the significance and limitations of the anion gap. Organic anions (albumin, lactate) are also discussed, albeit briefly. The suitability of anions for their role in neurotransmission and acid2base balance is outlined.

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Section: Sulphatementioning

confidence: 99%