Sulfapyridine and Its Sodium Salt

Pneumococcal Meningitis

“…Very young patients had a poor prognosis before penicillin became available (Cooke, 1941 ;Waring and Weinstein, 1948;Jackson, 1950), but the prognosis for infants when penicillin is used appears fairly good. With penicillin treatment, Waring and Weinstein (1948) noted a 69% recovery for patients under 2 years old (58 cases), while Nemir and Israel (1951) lost only one of nine infants, and Ross and Burke (1946) achieved a recovery of all nine infants. In the present series also the prognosis for infants with penicillin therapy was better than average (Table III).…”

“…Surgical treatment for the elimination of foci of infection in the ears, mastoids, or sinuses was regarded as a mainstay of treatment in pneumococcal meningitis before penicillin was available (Neal et al, 1940;Walker and James, 1945), but with the use of penicillin Smith et al…”

Pneumococcal Meningitis

“…Surgical treatment for the elimination of foci of infection in the ears, mastoids, or sinuses was regarded as a mainstay of treatment in pneumococcal meningitis before penicillin was available (Neal et al, 1940;Walker and James, 1945), but with the use of penicillin Smith et al (1946) never found such operations necessary in the acute phase and often not at all. Ross and Burke (1946) found no surgery necessary in their 19 cases.…”