Sulfadimethoxine in Prevention of Turkey Coccidiosis

Abstract

group averages were 2.8 each. In comparison, the average 4-week feed conversion of the exposed control group was 3.2.

Coccidiosis in the turkey

“…This has been demonstrated experimentally for lasalocid and monensin, although the results are not always consistent (Mitrovic et al, 1979;Potter et al, 1986;Czarnecki, 1990). No significant reductions in weight gain were found in young poults given twice the approved use level of amprolium, diclazuril, maduramicin, robenidine or sulfadimethoxine (Mitrovic, 1968;Joyner & Norton, 1972;Vanparijs et al, 1989a;McDougald et al, 1990;Mathis, 1993). A slight weight gain depression was found, however, with 6 parts/10 6 halofuginone (McDougald, 1986).…”

“…Sulfaguanidine was reported to possess curative properties if administered in the feed for two or three successive days, but experimental details were not provided (Marsden & Martin, 1946). Many other sulfonamides were subsequently shown to have anticoccidial activity (Moore, 1949;Morehouse, 1949b;Peterson, 1949;Boyer & Brown, 1953;Mitrovic, 1968;Reid, 1972); of these, sulfaquinoxaline was to prove the most useful. Amprolium was also widely employed (Cuckler et al, 1961).…”

“…Early studies with sulfonamides and amprolium are difficult to interpret because poults were challenged at least 2 weeks after drug withdrawal. Immunity could therefore have been acquired because of exposure to oocysts following cessation of medication (Horton- Smith & Long, 1961;Ball & Warren, 1963a,b;Mitrovic, 1968). Ionophores (maduramicin, monensin, and lasalocid) and amprolium did not interfere with the development of immunity (Reid et al, 1978;Wang & Ingle, 1992;Mathis, 1993;Mathis et al, 1997).…”

Safety of Sulfadimethoxine Potentiated Mixture (Rofenaid®), a New Broad Spectrum Coccidiostat-Antibacterial, in Turkeys

“…Sulfadimethoxine alone has been shown to be highly effective, therapeutically, against all pathogenic species of coccidia in chickens (0.05%) and turkeys (0.025%) when administered in the drinking water (Mitrovic and Bauernfeind, 1967) and efficacious in the prevention of turkey coccidiosis at 0.0125% in the feed (Mitrovic, 1968). Mitrovic (1967) reported that sulfadimethoxine was also effective in the therapy of fowl cholera in chickens (0.05%) and turkeys (0.025%) and infectious coryza in chickens (0.05%) when administered in the drinking water.…”

Safety and Compatibility of Sulfadimethoxine Potentiated Mixture (Ro 5–0013) , a New Broad Spectrum Coccidiostat-Antibacterial, in Chickens

“…Sulfadimethoxine alone has been reported to be highly effective, therapeutically, against all pathogenic species of coccidia in chickens (0.05%) and turkeys (0.025%) when administered in the drinking water (Mitrovic and Bauernfeind, 1967) and efficacious in the prevention of turkey coccidiosis at 0.0125% in the feed (Mitrovic, 1968). Mitrovic (1967) found that sulfadimethoxine was also effective in the therapy of fowl cholera in chickens (0.05%) and turkeys (0.025%) and infectious coryza in chickens (0.05%) when administered in the drinking water.…”