Abstract:Background: Recently, the mutual effects of tumor cells and the tumor immune microenvironment have been identified as key factors in promoting cancer progression. Sulfatase 2 (SULF2) encodes an extracellular endoglucosamine‑6-sulfatase, which could remodel the highly sulfated domains of heparan sulfate. The abnormal expression of SULF2 is reported to play an important role in the carcinogenesis of many kinds of cancer. However, the prognostic value of SULF2 and its correlation with immune cell infiltration in … Show more
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