Suitability of the isolated chicken eye test for classification of extreme pH detergents and cleaning products

Cazelle, Elodie; Eskes, Chantra; Hermann, Martina; Jones, Penelope; Maiello, Pauline; Prinsen, M.K.; Taylor, Hannah; Wijnands, Marcel V. W.

doi:10.1016/j.tiv.2014.12.020

Cited by 12 publications

(5 citation statements)

References 9 publications

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“…In order to separate fat deposits on surfaces of the technological equipment and objects of the environment of slaughter shops and meat processing enterprises, it is neces-sary that the agents show good sinking property that depends on the pH of solutions (Cazelle et al, 2015).…”

Section: Resultsmentioning

confidence: 99%

Activity of washing-disinfecting means “San-active” for sanitary treatment of equipment of meat processing enterprises in laboratory and manufacturing conditions

Салата

Kukhtyn²,

Pekriy³

et al. 2018

Ukr. Jour. of Vet. and Agr. Sci.

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The article presents the results of the research of the new detergent agent “San-active” for meat processing enterprises. It was established that “San-active” in the concentration from 0.3 to 2.0% is moderately alkaline (concentration of hydrogen ions is 11.44–12.7), at a concentration of 2.5% and above, with very alkaline pH ≥ 13.11 units. In the “San-active” detergent, at the concentration from 0.3 to 2.5%, the surface tension is 34.97–28.24 mN/m. The absorbability of the parts of the technological equipment with the solutions of the “San-active” means sharply increases with increasing concentration. At the temperature of solutions of the medium 19.0 ± 1.0 °С the angle of wetting decreases from 69.8 degrees. at a concentration of 0.3% to 50.5 degrees. at a concentration of 2.5% (in 1.4 times). It has been established that “San-active” in 0.5% concentration provides the bactericidal effect on test cultures of conditionally pathogenic bacteria, spore-forming microorganisms and fungi. The “San-active” agent at 0.5% concentration is bactericidal to S. aureus and E. faecalis cells that are in a biofilm in 10 minutes of exposition. For the inactivation of E. coli and P. aeruginosa cells in a biofilm, it is necessary that the “San-active” acts in a concentration not lower than 0.5% and not less than 30 minutes. The agent shows a washing effect on the evaluation of “good” at 0.5% concentration, and 1.0% and above the concentration on the score “excellent”. “San-active” in the concentration from 1.0 to 2.0% shows very weak corrosion activity on stainless steel. The use of “San-active” detergent for the sanitary treatment of equipment surfaces in the intestinal workshop at the concentration of the working solution 1.0–2.0% and the temperature 60 ± 5 °C for 20 minutes provides 99.9–100% efficiency of sanitary treatment.

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Section: Resultsmentioning

confidence: 99%

Activity of washing-disinfecting means “San-active” for sanitary treatment of equipment of meat processing enterprises in laboratory and manufacturing conditions

Салата

Kukhtyn²,

Pekriy³

et al. 2018

Ukr. Jour. of Vet. and Agr. Sci.

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“…Strongly alkaline degreasers are very corrosive and result in rust on the surfaces of metal equipment or machinery [48]. However, cleaning products with extreme pH values (pH>11.5) are very likely to be corrosive to the eyes and skin [49]. The surface tension and ODT for the optimized eco-friendly degreaser and the three commercial products were observed and calculated.…”

Section: A Comparative Study To Assess Eco-friendly Degreaser Perform...mentioning

confidence: 99%

Application of Response Surface Methodology in the Formulation of an Eco-friendly Degreaser using Rhamnolipid Biosurfactant

Muhamad Hissammuddin Shah Zainal Abidin,

Umi Aisah Asli,

Nor Dina Sakaria

et al. 2024

ARASET

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Formulating a bio-based degreaser emulsion can be challenging because it requires maximizing the performance to be as good as a commercial chemical-based product without compromising the cost and effect on the environment. This study aimed to develop an eco-friendly degreaser using natural Rhamnolipid biosurfactant through response surface methodology (RSM), which was then validated and assessed compared to chemical-based commercial products. The Plackett–Burman design (PBD) and Box–Behnken design (BBD) were used to screen and optimize factors for the formulation. From the PBD's result, the amount of Rhamnolipid, with other environmentally friendly ingredients of D-limonene, sodium citrate, and calcium carbonate, were shortlisted as significant factors in the formulation. Next, the BBD optimization study revealed that only rhamnolipid and sodium citrate significantly affected the two-way interaction of the factor on the result of the surface tension and oil displacement test (ODT). In the validation study, the experimental value was very close to the rate predicted by the model for the response surface tension and ODT (24.14 mN/m and 241 mm, respectively). A comparison of the performance with commercial products proved that this formulation was comparable to that commercial product. Overall, this study revealed that the effective eco-friendly degreaser formulation was successfully produced using a minimal amount of rhamnolipid biosurfactant with a response surface methodology as a tool.

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“…-The ICE test method can be used for the testing of substances and mixtures (OECD 2013b2018a, 2013d2018b;Cazelle et al, 2014Cazelle et al, , 2015.…”

Section: Applicabilitymentioning

confidence: 99%

“…In particular, the use of histopathology as an additional endpoint to the ICE test method was found to decrease the rate of false negatives (as observed with the ICE test method when used as a stand-alone) for the identification of UN GHS Cat. 1 for the limited applicability domain of non-extreme pH detergent and cleaning products (OECD, 2018b;Cazelle et al, 2014Cazelle et al, , 2015. Interestingly, these mixtures were mostly classified in vivo UN GHS Cat.…”

mentioning

confidence: 99%

Second Edition - Guidance Document on Integrated Approaches to Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation

2019

OECD Series on Testing and Assessment

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Suitability of the isolated chicken eye test for classification of extreme pH detergents and cleaning products

Cited by 12 publications

References 9 publications

Activity of washing-disinfecting means “San-active” for sanitary treatment of equipment of meat processing enterprises in laboratory and manufacturing conditions

Activity of washing-disinfecting means “San-active” for sanitary treatment of equipment of meat processing enterprises in laboratory and manufacturing conditions

Application of Response Surface Methodology in the Formulation of an Eco-friendly Degreaser using Rhamnolipid Biosurfactant

Second Edition - Guidance Document on Integrated Approaches to Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation

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