“…Compared with landbased crops, microalgae have a nutritional quality that is more similar to sh oil, especially in terms of proteins, lipids, vitamins, and minerals, and, hence, they are considered as a promising alternative to sh oil and could enhance sustainability in aquaculture [6]. Studies have shown that marine microalgae diets that are rich in long-chain polyunsaturated fatty acids (LC-PUFA), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), can improve the growth, nutritional performance, and fatty acid pro le of sh [3,7,8]. Moreover, Sheikhzadeh et al have found that dietary supplementation with 2.5% Spirulina platensis could improve mucosal immune responses and disease resistance in rainbow trout [9].…”