Suicide Prevention After Traumatic Brain Injury

Simpson, Grahame; Tate, Robyn; Whiting, Diane L.; Cotter, Rachel

doi:10.1097/htr.0b013e3182225250

Cited by 71 publications

(16 citation statements)

References 37 publications

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“…Cognitive behavioral interventions also have a growing body of evidence to support their efficacy for treating PTD,131–136 though to what extent any specific approach (eg, cognitive behavioral therapy27,134,135 and problem-solving treatments137) was better than another or better than traditional psychotherapy (eg, talk therapy and psychodynamic therapy) still remains to be determined 117,131. Isolating the “active ingredients” of behavioral interventions, particularly if different components are more or less effective for specific subtypes or subgroups of individuals with PTD, will inform clinical triage, training for practitioners, and systems of care.…”

Section: Discussionmentioning

confidence: 99%

A narrative literature review of depression following traumatic brain injury: prevalence, impact, and management challenges

Juengst¹,

Kumar²,

Wagner³

2017

PRBM

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Depression is one of the most common conditions to emerge after traumatic brain injury (TBI), and despite its potentially serious consequences it remains undertreated. Treatment for post-traumatic depression (PTD) is complicated due to the multifactorial etiology of PTD, ranging from biological pathways to psychosocial adjustment. Identifying the unique, personalized factors contributing to the development of PTD could improve long-term treatment and management for individuals with TBI. The purpose of this narrative literature review was to summarize the prevalence and impact of PTD among those with moderate to severe TBI and to discuss current challenges in its management. Overall, PTD has an estimated point prevalence of 30%, with 50% of individuals with moderate to severe TBI experiencing an episode of PTD in the first year after injury alone. PTD has significant implications for health, leading to more hospitalizations and greater caregiver burden, for participation, reducing rates of return to work and affecting social relationships, and for quality of life. PTD may develop directly or indirectly as a result of biological changes after injury, most notably post-injury inflammation, or through psychological and psychosocial factors, including pre injury personal characteristics and postinjury adjustment to disability. Current evidence for effective treatments is limited, although the strongest evidence supports antidepressants and cognitive behavioral interventions. More personalized approaches to treatment and further research into unique therapy combinations may improve the management of PTD and improve the health, functioning, and quality of life for individuals with TBI.

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Section: Discussionmentioning

confidence: 99%

A narrative literature review of depression following traumatic brain injury: prevalence, impact, and management challenges

Juengst¹,

Kumar²,

Wagner³

2017

PRBM

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“…Hopelessness is among the strongest psychological risk factors for suicide, and specific psychological treatments have been devised in order to address hopeless ideation [17]. It has been shown to an independent factor that distinguishes depressed individuals with suicidal ideation from depressed individuals without suicidal ideation [18•], and it has recently been implicated as a unique contributor in the contemplative phase of impulsive suicide attempts [19].…”

Section: Insomnia Hopelessness and Nightmares—modifiable Risk Factomentioning

confidence: 99%

The Link Between Suicide and Insomnia: Theoretical Mechanisms

McCall

Parker

2013

Curr Psychiatry Rep

161

104

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Insomnia has been established as a risk factor for depression and mental illness for decades, but a growing body of evidence has recently exposed insomnia to be an independent risk factor for suicide that encompasses all age ranges. This discovery has invigorated investigation to elucidate the relationship between insomnia and suicide, and over 20 studies reinforcing this association in adults have been published since 2010 alone. This article analyzes relevant research and emphasizes studies published within the last three years with the intent of proposing theoretical mechanisms explaining the link between suicide and insomnia. These mechanisms may then be used as targets for future investigation of treatment.

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“…We suggest that either the BDI or the SCL-90-R, which asks about thoughts of ending life, is adequate for studies where suicide risk is not a major focus. For studies where suicidal ideation is a matter of specific interest, we join with Dennis et al (250) in recommending the Beck Hopelessness Scale (251, 252) that was also used by Simpson and Tate (238) and Simpson et al (253) in studies of suicide prevention after TBI.…”

Section: Additional Assessments Recommended For Studies Investigatingmentioning

confidence: 99%

Patient Characterization Protocols for Psychophysiological Studies of Traumatic Brain Injury and Post-TBI Psychiatric Disorders

Rapp¹,

Rosenberg²,

Keyser³

et al. 2013

Front. Neurol.

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Psychophysiological investigations of traumatic brain injury (TBI) are being conducted for several reasons, including the objective of learning more about the underlying physiological mechanisms of the pathological processes that can be initiated by a head injury. Additional goals include the development of objective physiologically based measures that can be used to monitor the response to treatment and to identify minimally symptomatic individuals who are at risk of delayed-onset neuropsychiatric disorders following injury. Research programs studying TBI search for relationships between psychophysiological measures, particularly ERP (event-related potential) component properties (e.g., timing, amplitude, scalp distribution), and a participant’s clinical condition. Moreover, the complex relationships between brain injury and psychiatric disorders are receiving increased research attention, and ERP technologies are making contributions to this effort. This review has two objectives supporting such research efforts. The first is to review evidence indicating that TBI is a significant risk factor for post-injury neuropsychiatric disorders. The second objective is to introduce ERP researchers who are not familiar with neuropsychiatric assessment to the instruments that are available for characterizing TBI, post-concussion syndrome, and psychiatric disorders. Specific recommendations within this very large literature are made. We have proceeded on the assumption that, as is typically the case in an ERP laboratory, the investigators are not clinically qualified and that they will not have access to participant medical records.

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Suicide Prevention After Traumatic Brain Injury

Abstract: This trial provides initial evidence for the efficacy of a psychological intervention in reducing hopelessness among long-term survivors with severe TBI.

Cited by 71 publications

References 37 publications

A narrative literature review of depression following traumatic brain injury: prevalence, impact, and management challenges

A narrative literature review of depression following traumatic brain injury: prevalence, impact, and management challenges

The Link Between Suicide and Insomnia: Theoretical Mechanisms

Patient Characterization Protocols for Psychophysiological Studies of Traumatic Brain Injury and Post-TBI Psychiatric Disorders

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