Suicidal ideation and physical illness: Does the link lie with depression?

Sanna, Livia; Stuart, Amanda L; Pasco, Julie A.; Kotowicz, Mark A.; Berk, Michael; Girardi, Paolo; Williams, Lana J.

doi:10.1016/j.jad.2013.10.008

Cited by 35 publications

(28 citation statements)

References 33 publications

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“…It is noteworthy that several cases of patients with skin diseases having either attempted or completed suicide have been reported by dermatologists (13,44), and even patients with AD with mild symptoms were reported to experience suicidal ideation (39). Understanding the role of medical conditions in suicidal ideation is complex (45), but several hypotheses have been suggested to explain the relationship between AD and the risk of suicidal behaviour (37). Above all, a depressive mood caused by cosmetic disfigurement and changes in body image was frequently reported to be associated with suicidal ideation, although other psychological problems, such as stress and sleep difficulties, also need to be considered (33,37,38).…”

Section: Suicidal Ideationmentioning

confidence: 99%

Psychological Health Status and Health-related Quality of Life in Adults with Atopic Dermatitis: A Nationwide Cross-sectional Study in South Korea

B³

et al. 2018

Acta Derm Venerol

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Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Patients with AD often experience psychological distress and poor health-related quality of life (HRQoL). The aim of this study was to investigate the association of several psychological health statuses and poor HRQoL in an adult population with AD in South Korea. A total of 37,578 adults who participated in the Korean National Health and Nutrition Examination Survey, a nationwide, population-based, cross-sectional health survey between 2008 and 2013 were included. HRQoL was assessed by EuroQoL (EQ) 5-dimension questionnaire and EQ-visual analogue scale scores. Multiple logistic regression analysis was performed to identify the association of stress, sleep duration, depressive mood, depression, suicidal ideation, and HRQoL with AD relative to matched controls. After adjusting in patients with AD confounding factors, stress, depressive mood, depression, suicidal ideation and poor HRQoL were significantly associated with AD. Dermatologists should be concerned with improving HRQoL and managing the psychological health status of adult patients with AD.

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Section: Suicidal Ideationmentioning

confidence: 99%

Psychological Health Status and Health-related Quality of Life in Adults with Atopic Dermatitis: A Nationwide Cross-sectional Study in South Korea

B³

et al. 2018

Acta Derm Venerol

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“…Original sources cited within articles were retrieved when necessary. English‐language articles examining the association of psoriasis with various aspects of suicidality were identified (Table ) (Abuabara et al, ; Chi et al, ; Dalgard et al, ; Egeberg et al, ; Friedman et al, ; Gupta et al, ; Gupta & Gupta, ; Kimball et al, ; Kimball et al, ; Krueger et al, ; Kurd et al, ; Lamb et al, ; Picardi et al, ; Pompili et al, ; Pompili et al, ; Rapp et al, ; Sanna et al, ; Sharma et al, ; Singh et al, ; Singhal et al, ; Svedbom et al, ; Wu et al, ; Zachariae et al, ).…”

Section: Methodsmentioning

confidence: 99%

“…Several studies suggest a relationship between psoriasis and an increased risk of suicidality (Dalgard et al, ; Kurd et al, ; Singh et al, ; Zachariae et al, ), with psoriasis having a stronger association with an increased risk than other dermatologic conditions (Gupta & Gupta, ; Picardi et al, ; Pompili et al, ; Pompili et al, ). However, other studies, including a recent population‐based cohort study of over 68,000 psoriasis patients, have not found a significant association (Abuabara et al, ; Egeberg et al, ; Kimball et al, ; Sanna et al, ; Svedbom et al, ; Wu et al, ). In 2017, two meta‐analyses by Chi et al and Singh et al examined the overall risk of SIB in psoriasis patients utilizing much of the available literature (Table ).…”

Section: Psoriasis and Suicidalitymentioning

confidence: 97%

“…In the available literature, several risk factors for increased suicidality have been identified in psoriasis patients. These risk factors include young age (Egeberg et al, ; Krueger et al, ; Kurd et al, ; Rapp et al, ; Singh et al, ; Singhal et al, ), concomitant psychiatric illness (Lamb et al, ; Picardi et al, ; Sanna et al, ), and increased severity of disease (Egeberg et al, ; Gupta et al, ; Kurd et al, ; Rapp et al, ; Singh et al, ).…”

Section: Psoriasis and Suicidalitymentioning

confidence: 99%

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Psoriasis and suicidality: A review of the literature

Liang

Cohen

2018

Dermatologic Therapy

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Psoriasis is a chronic systemic inflammatory skin disease, which has been associated with an increased risk of numerous medical and psychiatric comorbidities, including suicidality. Suicidality, which can be divided into the categories of suicidal ideation, suicide attempt, and completed suicide, is highly prevalent in the psoriasis population, and multiple studies have been published on the subject of psoriasis and suicidal ideation and behavior (SIB), including two recent metaanalyses. However, the available literature is limited and inconsistent, and the association between the two remains incompletely understood. The present review aims to cohesively synthesize and summarize the available evidence, while making a clinically relevant distinction between the sub-categories of suicidality, by examining not only the epidemiology of the association but also the plausible molecular mechanisms and the potential influence of biologic therapies. Additionally, this review aims to critically examine and understand the potential contribution of depression in the psoriasis and suicidality relationship. This will allow us to better understand the complex and multi-faceted relationship between psoriasis and suicidality, to identify those who may be most at risk for SIB, to make evidence-based clinical decisions regarding treatment and management, and to more completely address the needs of psoriasis patients. K E Y W O R D Spsoriasis, suicidal ideation and behavior, suicidality

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“…Whether the probability of suicide is high in patients with chronic medical conditions or whether it is noted only in patients with specific disorders remains controversial (11). Sanna et al reported an association between suicidality and several medical disorders; however, no association was noted between suicidality and pulmonary disease (12).…”

Section: Introductionmentioning

confidence: 99%

Suicide Attempt and Suicidal Drug Overdose in Chronic Obstructive Pulmonary Disease Patients With or Without Depression

Lin¹,

Harnod

Lin

et al. 2020

Front. Psychiatry

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Background: To determine differences in the incidence and risks of suicide attempt (SA) and suicidal drug overdose (SDO) between chronic obstructive pulmonary disease (COPD) patients with and without comorbid depression by using data from Taiwan's National Health Insurance Research Database. Methods: We analyzed the data of patients aged ≥20 years who had received a COPD diagnosis between 2000 and 2012. These COPD patients were divided into those with and without depression, and they were compared against a cohort from the general population. We calculated adjusted hazard ratios and the corresponding 95% confidence intervals for SA and SDO in the three cohorts after adjustment for age, sex, and comorbidities. Results: Until the end of 2012, 5.81% of patients with COPD developed depression. The incidence of SA and SDO in COPD patients with and without depression was 29.7 and 4.69 per 10,000 person-years and 71.2 and 20.9 per 10,000 person-years, respectively. COPD patients with depression had 13.6-and 10.0-fold higher risks of SA and SDO, respectively, than did controls. Particularly, an increased risk of SA caused by the enhancement effects of depression on COPD was noted in patients aged less than 50 years. Conclusion: SA and SDO risks are extremely high in Taiwanese COPD patients with depression. Our findings suggest that clinicians should be aware that for COPD patients with comorbid depression, prescribing a large amount of medications may be associated with SA risk through SDO.

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Suicidal ideation and physical illness: Does the link lie with depression?

Abstract: Health care professionals should focus on identification, assessment and management of suicidal ideation in the medically ill in patients both with and without MDD.

Cited by 35 publications

References 33 publications

Psychological Health Status and Health-related Quality of Life in Adults with Atopic Dermatitis: A Nationwide Cross-sectional Study in South Korea

Psychological Health Status and Health-related Quality of Life in Adults with Atopic Dermatitis: A Nationwide Cross-sectional Study in South Korea

Psoriasis and suicidality: A review of the literature

Suicide Attempt and Suicidal Drug Overdose in Chronic Obstructive Pulmonary Disease Patients With or Without Depression

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