Suicidal Behavior in the Older Patient with Schizophrenia

Kasckow, John; Montross, Lori P.; Prunty, Laurie; Fox, Lauren; Zisook, Sidney

doi:10.2217/ahe.11.23

Cited by 17 publications

(10 citation statements)

References 120 publications

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“…Suicidal behavior is a common complication in Schizophrenic patients and has various risk factors associated with this problem [1][2][3]. The most common ones are younger age, higher intellectual level, depression, hopelessness, and greater insight into the illness.…”

Section: Discussionmentioning

confidence: 99%

“…Around 10% of the Schizophrenic patient population dies due to suicide. There are several risk factors accountable for the suicidal behavior in this patient population [2][3][4][5][6]. The most common ones are white ethnicity, younger age, unmarried, higher intellectual level, social isolation, gradual onset of illness, hopelessness, co-morbid substance abuse, previous hospitalizations, previous suicide attempts, family history of suicide, family stress, impulsivity, positive symptoms of schizophrenia, unemployment, prolonged illness, the greater insight of the illness and others [7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

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Suicidal Behavior and Medication Adherence in Schizophrenic Patients

Warriach¹,

Sanchez-Gonzalez²,

Ferrer³

2021

Cureus

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Suicide is one of the potential complications in the Schizophrenic patient population. This review article deals with the significance of antipsychotic medication compliance in decreasing suicidal behavior and hospitalizations in Schizophrenic patients. The medication adherence with second-generation antipsychotics (SGA) like clozapine and long-acting injectables (LAIs) like paliperidone is associated with decrease suicidal behavior and all-cause mortality in Schizophrenic patients. Concomitant treatment of depression and substance abuse disorder in this patient population is also associated with decreasing all-cause mortality and hospitalizations. On the other hand, long-term benzodiazepine use is associated with increase mortality in Schizophrenic patients. We also discuss some important physician intervention strategies to improve medication adherence in Schizophrenic patients like motivational interviewing (MI), behavioral tailoring (BT), and psychosocial interventions like cognitive behavior therapy (CBT).

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Suicidal Behavior and Medication Adherence in Schizophrenic Patients

Warriach¹,

Sanchez-Gonzalez²,

Ferrer³

2021

Cureus

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“…Suicidal thoughts are much more common in patients with major psychiatric disorders compared with members of the general population. Accordingly, suicidal thoughts occur in 79% of depressed phases of BPD and approximately 50% during the course of schizophrenia (25.5% in the prodromal phase of schizophrenia) [17][18][19][20]. Alcohol dependence is associated with a 4.6-fold greater risk of suicidal thoughts [21].…”

Section: Suicidal Behavior In General and Psychiatric Populationsmentioning

confidence: 99%

Effects of smoking on health outcomes in bipolar disorder with a special focus on suicidal behavior

Döme¹,

Gonda²,

Rihmer³

2012

Neuropsychiatry

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Bipolar disorder (BPD) is a common and devastating mental illness. The life expectancy for patients with BPD is significantly less than for members of the general population. The main causes for excess mortality in bipolar patients are cardiovascular disorders and, to a lesser degree, suicide. Smoking/nicotine dependence is a highly comorbid condition in patients with BPD and it has a well-known role in the etiopathogenesis of cardiovascular disorders and, according to results from the general population, is associated with elevated risk of suicidal behavior. In this literature review, the results of studies on the abovementioned associations and also the effects of comorbid smoking on clinical characteristics of BPD are summarized, with a special focus on suicidal behavior. To identify peer-reviewed research papers and reviews, databases (PubMed and Web of Science) and forward/backward citation searches were used with the following keywords: 'smoking', 'tobacco', 'nicotine', 'suicide' and 'BPD'. Only publications in English were considered.

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“…It is a well-known fact that suicide is a major cause of death in Western countries [ 1 ]. Most of the available studies suggest that nearly 70–95% of suicide victims have a mental disorder, the most common being affective disorders and schizophrenia [ 2 ]. Some studies have estimated a frequency of suicidal ideation in schizophrenic patients around 50% [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…Most of the available studies suggest that nearly 70–95% of suicide victims have a mental disorder, the most common being affective disorders and schizophrenia [ 2 ]. Some studies have estimated a frequency of suicidal ideation in schizophrenic patients around 50% [ 2 , 3 ]. In addition, 20–50% of these patients reported suicidal attempts in their lifetime [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Suicidal Ideation and Suicidal Behaviour in Delusional Disorder: A Clinical Overview

et al. 2014

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Background. Most of the existing studies suggest that suicide is one of the leading causes of premature death in patients with chronic psychotic disorders. However, very few studies have specifically investigated suicidal behaviour in patients with delusional disorder. Thus, our objective was to review the literature regarding the percentage of lifetime ideation and suicidal behaviour in delusional disorder in order to provide suggestions for clinical practice. Methods. MEDLINE and PsycINFO were searched from January 1980 to September 2012 using the following keywords: delusional disorder, paranoia, suicidal ideation, and suicidal behaviour. Results. A total of 10 studies were identified and included in the review. The percentage of suicidal behaviour in delusional disorder was established between 8 and 21%, which is similar to schizophrenia. Suicidal ideation and suicide attempts were more frequent in patients showing persecutory and somatic delusions in the reviewed studies. Conclusions. To the best of our knowledge this is the first attempt to specifically review the suicide phenomenon in patients with delusional disorder. Interestingly, our results support the notion that percentages of both suicidal ideation and behaviour in delusional disorder are similar to patients with schizophrenia.

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Suicidal Behavior in the Older Patient with Schizophrenia

Cited by 17 publications

References 120 publications

Suicidal Behavior and Medication Adherence in Schizophrenic Patients

Suicidal Behavior and Medication Adherence in Schizophrenic Patients

Effects of smoking on health outcomes in bipolar disorder with a special focus on suicidal behavior

Suicidal Ideation and Suicidal Behaviour in Delusional Disorder: A Clinical Overview

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