Suicidal behavior in bipolar mood disorder: clinical characteristics of attempters and nonattempters

Does first episode polarity predict risk for suicide attempt in bipolar disorder?

“…This was not explained by years ill, lifetime number of major depressive episodes, or BD-I vs. II/NOS subtype. Hostility was associated with suicide attempt risk, consistent with previous reports from our group (Grunebaum et al, 2006;Oquendo et al, 2000). Reasons for living appeared to be an important protective factor.…”

Pleiotropic Effects of Drosophila neuralized on Complex Behaviors and Brain Structure

“…The behavioral phenotypes of neur mutant flies are reminiscent of those encountered in patients suffering from neuropsychiatric and neurodegenerative disorders, including reduced responsiveness to environmental stimuli and increased aggressive behavior. Neurodegenerative and neuropsychiatric disorders ranging from bipolar disorder, schizophrenia, and antisocial personality disorder to Alzheimer's and Parkinson's disease are often accompanied by behavioral alterations, such as indifference to stimuli, hypokinesia, hyperactivity, and aggression (Paveza et al 1992;Aarsland et al 1999;Moran 1999;Oquendo et al 2000;Brieden et al 2002;Haller and Kruk 2006). Apathy and aggressive behavior have a catastrophic impact on the social functioning of neuropsychiatric patients.…”

Diagnóstico e tratamento dos estados mistos

“…7,16,24,[29][30][31][32][33] MS are associated with higher rates of impulsiveness and suicidality (suicide ideation, attempts and act). [34][35][36][37] Therefore, the disease with this pattern shows higher morbidity and mortality.…”