Sugary beverages consumption and latent autoimmune diabetes in adults: systematic review and meta-analysis

Abstract

Introduction. Sugary beverages consumption (SBC) has amplified globally. SBC is associated with and leads to obesity and chronic diseases, nonetheless the role of SBC in development of autoimmune disorders such as latent autoimmune diabetes in adults (LADA) has not been addressed adequately among the different ethnic groups. We conducted this meta-analysis to compare the random effect of SBC intake on the risk of development of LADA. Methods. We scrutinized the MEDLINE database up until January 2019 for articles addressing the association between sugary beverages, coffee consumption and LADA. We found 6 studies all of them addressed the LADA. We have included them in the meta-analysis and compared the random effect of SBC from the uppermost to the lowermost quantiles parallel to the risk of LADA. Results. According to the research conducted, and data extracted, which involved 15027 contributors and 1862 patients with LADA, the participants in the uppermost quantile of SBC intake (used 1-2 servings per day in most cases) were at risk of developing LADA more than those in the lowermost quantile (≤ 1 serving per month) (odds ratio [OR] 1.37 [95% CI 1.23-1.52]). Conclusion. According to the meta-analysis resultsexcessive SBC intake may increase the risk of development of latent autoimmune diabetes in adults. However, no definite conclusions could be drawn due to heterogeneous data from low quality researches and the analysis was based on observational and casecontrol studies only.

Dietary sugar consumption and health: umbrella review

“… 62 The highest versus lowest sugar sweetened beverage consumption was also significantly associated with a higher risk of latent autoimmune diabetes in adults (odds ratio 1.26, 1.12 to 1.41) ( fig 2 ; fig3 ). 30 …”

“…Dietary sugar consumption had harmful associations with endocrine and metabolic outcomes, including changes in body mass index in children, 53 changes in body weight, 53 changes in body weight (one year), 53 gout, 11 13 58 high density lipoprotein cholesterol, 60 hyperuricaemia, 11 59 latent autoimmune diabetes in adults, 30 low density lipoprotein cholesterol, 60 metabolic syndrome, 61 obesity in children, 3 obesity in adults, 1 serum uric acid, 57 type 2 diabetes mellitus, 6 liver fat accumulation, 54 and muscle fat accumulation. 54 In addition, harmful associations between dietary sugar consumption and cardiovascular outcomes were also observed, including coronary heart disease, 10 cardiovascular disease, 8 cardiovascular disease mortality, 68 71 hypertension in children and adolescents, 69 hypertension in adults, 70 myocardial infarction, 66 change in systolic blood pressure in children and adolescents, 69 and stroke.…”

“… 29 The 2007 annual report of the Coca-Cola company revealed that the consumption of sugar sweetened beverages in India and China increased by 14% and 18%, respectively, in one year. 30 In 2018 a cross sectional survey conducted among Chinese primary and junior high school students showed that sugar sweetened beverages provide 10-15% of the total calorie consumption of school students. 31 Data from the National Health and Nutrition Examination Survey (NHANES) showed that, in 2009-10, sugar sweetened beverage consumption contributed 8% and 6.9% of daily energy intake among children/adolescents and adults, respectively, in the US.…”

Psychometric properties of the Chinese version of the sugar-sweetened beverages media literacy scale for undergraduates

“…Evidence, including prospective epidemiological studies, suggests that SSB intake is associated with obesity, both in adults and children (1,(10)(11)(12)(13)(14)(15)(16). Due to the rapid absorption of liquid carbohydrates, SSB may trigger glucose intolerance and insulin resistance and increase the risk of developing metabolic diseases such as latent autoimmune diabetes in adults, type 2 diabetes mellitus and metabolic syndrome in adults by increasing the dietary glycemic load in the presence of high consumption (1,(11)(12)(13)(17)(18)(19)(20). SSB intake, even at low calorie levels, promotes higher triglyceride concentrations and is associated with adverse levels of inflammation and serum C-reactive protein, a biomarker of cardiovascular risk, and may lead to an increased risk of cardiovascular morbidity and mortality (13,16,(20)(21)(22)(23)(24).…”

“…The transition from home to college may lead to poor choices in undergraduates' diet (40)(41)(42)(43). They are in an obesogenic environment, have access to an all-you-can-eat cafeteria, where the food is often high in fat and sugar (17)(18)(19). In terms of promoting sound eating habits, undergraduates represent an important subgroup of young adults due to the challenges they face in making healthy choices (20).…”