2005
DOI: 10.1136/jramc-151-01-02
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Sugar Solutions Used In Resuscitation

Abstract: Although recent studies have shown that the timing of volume replacement deserves careful consideration (56), which fluid to use is less clear, with the perennial debate of crystalloid v colloid and now colloid v colloid still unresolved. This review has examined three sugar solutions, two colloids and one crystalloid. In general, all three agents are unhelpful in the immediate resuscitation of hypovolaemic trauma by virtue of a combination of pathophysiology and side effects. Dextran solutions and mannitol ar… Show more

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Cited by 3 publications
(3 citation statements)
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“…(Systolic BP> 100mmHg) The continued application of this protocol in the hospital setting is still not established [7]. The use of artificial colloids is not without risk, due to the pathophysiological processes (capillary leak and inflammation) involved in the response to tissue trauma [8]. The use of lower-volumes of resuscitation fluid would seem sensible in the case of chest trauma in particular and the use of hypertonic saline may have some place; although it has certainly not gained universal acceptance [9].…”
Section: Acute Fluid Resuscitationmentioning
confidence: 99%
“…(Systolic BP> 100mmHg) The continued application of this protocol in the hospital setting is still not established [7]. The use of artificial colloids is not without risk, due to the pathophysiological processes (capillary leak and inflammation) involved in the response to tissue trauma [8]. The use of lower-volumes of resuscitation fluid would seem sensible in the case of chest trauma in particular and the use of hypertonic saline may have some place; although it has certainly not gained universal acceptance [9].…”
Section: Acute Fluid Resuscitationmentioning
confidence: 99%
“…It is generally used in patients with clinical signs of trans-tentorial herniation.The associated diuretic and volume depleting effect of mannitol may be counter productive where there is no clear clinical indication for its use (32).…”
Section: Mannitolmentioning
confidence: 99%
“…Rather controversially some have pointed out that the amount of fluid to be used in resuscitation has been overshadowed by questions about the choice of fluid; suggesting that this is driven by commercial interests of pharmaceutical companies looking for a market share in resuscitation fluid (Roberts et al, 2001). Whatever the merits of this argument, the use of artificial colloids is not without risk, due to the pathophysiological processes (capillary leak and inflammation) involved in the response to tissue trauma (Parkhouse, 2005). Intuitively the use of lower-volumes of resuscitation fluid would seem to make sense in the case of chest trauma in particular and the use of hypertonic saline may have some place; although it has certainly not gained universal acceptance (Myers, 1997).…”
Section: Timing Of Fracture Fixationmentioning
confidence: 99%