Sugar or High Fructose Corn Syrup—What Should Nurses Teach Patients and Families?

Sobel, Linda L; Dalby, Elizabeth

doi:10.1111/wvn.12027

Cited by 3 publications

(2 citation statements)

References 19 publications

(36 reference statements)

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“…The form of fructose commonly used by industry for these beverages is HFCS. This type of sugar has been shown to have detrimental effects on health [Sobel and Dalby, 2014; Chan et al, 2014]. Recent in vitro studies have shown that HFCS has a higher acidogenic potential than sucrose [Ma et al, 2013].…”

Section: Discussionmentioning

confidence: 99%

Association between Type, Amount, and Pattern of Carbohydrate Consumption with Dental Caries in 12-Year-Olds in Puerto Rico

et al. 2016

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Objective: To identify the types, food sources, and pattern of carbohydrates that significantly contribute to dental caries in Puerto Rican children. Methods: As part of an island-wide cross-sectional oral health study in 1,587 twelve-year-olds, diet intake was assessed in a representative subset (n = 801) with a 24-hour dietary recall. Carbohydrate intake was quantified using a computer-based diet analysis program. Caries was assessed using the National Institute of Dental and Craniofacial Research diagnostic criteria. Odds ratios were used to associate carbohydrate intake quartiles with caries, after controlling for important confounders. Results: A total of 723 subjects had complete data. Most were females (54%) and attended public schools (77%). The caries prevalence was 33%. The highest quartile intake for the following sugars significantly increased the odds of caries compared to the lowest quartile: total carbohydrates (OR = 1.93, 95% CI = 1.08-3.46), total sugars (OR = 1.88, 95% CI = 1.01-351), sucrose (OR = 2.05, 95% CI = 1.13-3.70), fructose (OR = 1.95, 95% CI = 1.05-3.62), and inositol (OR = 2.52, 95% CI = 1.38-4.63). The main food sources of these sugars were juices, including natural juices with no added sugars, and sweetened beverages. The odds of caries also increased significantly in children whose 10% of total energy intake was from total sugars (OR = 3.76, 95% CI = 1.03-13.7). Conclusion: After adjusting for important caries risk factors, total carbohydrates, total sugars, ≥10% kilocaloric energy from total sugars, and sucrose, fructose, and inositol intake significantly increased caries risk. Our findings can help raise awareness about the potential caries risk from the main sources of these sugars, natural fruit juices and sweetened beverages, which are consumed in great quantities in many societies.

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Section: Discussionmentioning

confidence: 99%

Association between Type, Amount, and Pattern of Carbohydrate Consumption with Dental Caries in 12-Year-Olds in Puerto Rico

et al. 2016

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“…HFCS is a fructose-glucose liquid sweetener alternative to sucrose first introduced to the food and beverage industry in the 1970s, and containing 42% to 55% fructose and glucose, depending on the application (7,8). There are many reports about the different physiological effects of fructose and glucose.…”

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confidence: 99%

Novel Biomarker Establishment for Evaluation of Excessive Fructose Consumption Using a Rat Model

Suzuki

Kondo

Toyoda

et al. 2023

In Vivo

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Background/Aim: The habitual consumption of excessive fructose is associated with the onset and progression of lifestyle-related diseases, such as nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the physiological changes observed when consuming a diet containing excessive fructose on the viewpoints of hepatotoxicity biological markers using a rat model and explored the biomarker candidates that could detect the effects of excessive fructose intake at an early stage. Materials and Methods: Male rats were fed 63% high fructose diet (HFrD) ad libitum and their blood samples were collected before and at 1, 2, 3, and 4 weeks after allocation. The plasma biochemical parameters, hepatotoxic enzyme activities including alkaline phosphatase (ALP) isozymes were analyzed. Results: HFrD consumption for 4-weeks created NAFLD-like symptoms, including elevated plasma lipid parameters and hepatotoxicity markers, as well as fat accumulation in the liver compared with rats consuming a control diet. Alanine aminotransferase (ALT) and glutamate dehydrogenase (GLDH) were increased from the 3 rd and 2 nd weeks, respectively, but no changes were observed on ALP activity. However, the daily consumption of the HFrD increased the plasma activities of liver-type ALP isozyme, and decreased plasma small intestinaltype ALP isozyme soon after the start of feeding. Conclusion: ALP isozyme analysis in combination with GLDH and ALT activities in the plasma samples could be a useful tool to detect the physiological changes induced by excessive fructose intake at an early stage of the development of NAFLD.

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Review of a causal role of fructose-containing sugars in myocardial susceptibility to ischemia/reperfusion injury

et al. 2017

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Sugar or High Fructose Corn Syrup—What Should Nurses Teach Patients and Families?

Abstract: The evidence suggests that fructose, found in both table sugar and HFCS, has a negative effect on health outcomes. Clinicians should teach patients and families that all sugar consumption should be closely monitored and kept below the 40 g/day recommended by the World Health Organization.

Cited by 3 publications

References 19 publications

Association between Type, Amount, and Pattern of Carbohydrate Consumption with Dental Caries in 12-Year-Olds in Puerto Rico

Association between Type, Amount, and Pattern of Carbohydrate Consumption with Dental Caries in 12-Year-Olds in Puerto Rico

Novel Biomarker Establishment for Evaluation of Excessive Fructose Consumption Using a Rat Model

Review of a causal role of fructose-containing sugars in myocardial susceptibility to ischemia/reperfusion injury

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