Sugar and Wound Healing

Gordon, H.; Middleton, K.; Seal, D.V.; Sullens, K.; Quatraro, A; Minei, A.; Donzella, C.; Caretta, F.; Consoli, Gianluca; Giugliano, Dario; Addison, Mark K; Walterspiel, JuanN.

doi:10.1016/s0140-6736(85)90026-1

Cited by 36 publications

(16 citation statements)

References 2 publications

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“…Polysaccharides such as honey and sucrose have also been used to facilitate wound cleansing. Granulated or icing sugar has been used successfully 14,15 interest has just been focused on the use of a sugar paste containing polyethylene glycol 400 and hydrogen peroxide 16,17,18 . A significant development of dressing sloughy wounds is the use of larva therapy (maggots) for the rapid removal of slough and necrotic tissue from wounds such as leg ulcers, pressure sores, and diabetic foot ulcer 19 .…”

Section: Discussionmentioning

confidence: 99%

Wound dressing where there is limitation of choice

Rahman¹,

Adigun²,

Yusuf³

et al. 2010

Nigerian Journal of Surgical Research

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Background Many sophisticated dressings are available to the wound care practitioner in the developed countries. These materials are made from a wide range of products like polyurethane, salts of alginic acid and other gelable polysaccharides. The situation is different in the developing countries where what is commonly available to wound care provider are traditional agents such as sodium hypochlorite, hydrogen-peroxide, cetrimide solution, chlorhexidine and others. The aim of this study is to reappraise the problem of limitation of wound dressing selection in the developing countries and to sensitize the wound care practitioner on the use of the commonly available products based on the needs of a different wound or even the same wound throughout its healing course. Patients and methods Patients attending the General Outpatient Department (GOPD) of our hospital for wound dressing were used for the study. Five surgeons who are familiar with wound care management visited the dressing unit of the GOPD daily for one week in October 2005. A proforma was designed where information on each of the patient was recorded. Results Fifty-three patients attended the dressing unit of our GOPD during the study period. Twenty-six patients (49.1%) had their wounds dressed with hypochlorite solution (Eusol), seventeen patients (32.1%) had their wounds dressed with honey and two patients, wound were being dressed with hydrogen peroxide. Conclusion While we are still awaiting the availability of the newer products in the developing countries, we should make use of the traditional products that are readily available to us according to the

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Section: Discussionmentioning

confidence: 99%

Wound dressing where there is limitation of choice

Rahman¹,

Adigun²,

Yusuf³

et al. 2010

Nigerian Journal of Surgical Research

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“…In premodern times, the idea that sugar can facilitate the healing of wounds has been documented. 10,11 Mesopotamians were known to wash wounds with water or milk and subsequently dress them with honey or resin. Mesopotamians also documented the severity of wounds and which conditions were optimal for facilitating the rate at which the wounds would heal.…”

Section: Sugar As a Wound-healing Modalitymentioning

confidence: 99%

“…45 Sugar and sugar pastes can achieve this environment and contribute the mechanical debridement of the wound bed. 11,46 This moist environment is achieved by sugar forming hydrogen bonds with wound exudate, causing the water activity of the sugar at the wound surface to rise. 47 This in turn produces a moist environment for angiogenesis to occur.…”

Section: Case Studies Of Sugar Used To Treat Diabetic Ulcersmentioning

confidence: 99%

Use of Sugar on the Healing of Diabetic Ulcers: A Review

Biswas

Bharara

Hurst

et al. 2010

J Diabetes Sci Technol

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Abbreviation: (DFU) diabetic foot ulcersKeywords: diabetic foot ulcers, sugar, wound healing AbstractWith the advent of several innovative wound care management tools, the choice of products and treatment modalities available to clinicians continues to expand. High costs associated with wound care, especially diabetic foot wounds, make it important for clinician scientists to research alternative therapies and optimally incorporate them into wound care protocols appropriately. This article reviews using sugar as a treatment option in diabetic foot care and provides a guide to its appropriate use in healing foot ulcers. In addition to a clinical case study, the physiological significance and advantages of sugar are discussed.

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“…Since enterococci are tolerant to penicillin, an aminoglycoside must be administered in addition to penicillin to obtain synergistic bactericidal activity (2). It has been reported that between 29 % and 81% of enterococci show high-level resistance to streptomycin; the combination of penicillin with streptomycin does not act synergistically against these isolates (3,4). Penicillin acts synergistically with gentamicin against most streptomycin-resistant enterococci and this combination has been recommended for treating patients infected with these organisms (5).…”

Section: Gentamiein-resistant Enterococcus Faecalismentioning

confidence: 99%

Successful treatment of chronically infected wounds with sugar paste

Tanner

Owen

Seal

1988

Eur. J. Clin. Microbiol. Infect. Dis.

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A sugar and polyethylene glycol paste is introduced which has marked antimicrobial activity and is available in thick and thin forms. The paste was used to treat 20 patients with chronically infected abdominal and perineal wounds that had failed to respond to conventional forms of treatment. Complete healing was achieved in 19 patients. The paste was especially effective in the treatment of large abscess cavities with small external openings. It was inexpensive, and easy and painless to apply.

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Sugar and Wound Healing

Cited by 36 publications

References 2 publications

Wound dressing where there is limitation of choice

Wound dressing where there is limitation of choice

Use of Sugar on the Healing of Diabetic Ulcers: A Review

Successful treatment of chronically infected wounds with sugar paste

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