“…Nonopsonic phagocytosis is a crucial mechanism for host control during the initial stages of infection, and mouse models indicate that this process may dictate colonization efficiency at the onset of P. aeruginosa challenge (4). Whereas recent reports and reviews have detailed various other components of P. aeruginosa respiratory disease, such as pulmonary edema, humoral immunity, and therapeutic avenues (10,16,20,31,32,46,51,61,73,88,96,102,110,122), this review will spotlight the current state of knowledge in nonopsonic phagocytic recognition and response mechanisms to P.…”