Suffocative Goiter in the Newborn

Handelsman, Jacob C.; Sussman, Harold I.

doi:10.1097/00000658-195701000-00012

Cited by 7 publications

(2 citation statements)

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“…Positive ethics requires professionals to recognise personal values and motives via reflection and to anchor decisions in overarching ethical principles, such as virtue ethics. 71 According to Handelsman and his co-authors "virtue ethics" are particularly useful for positive ethics because they help to fulfil both personal and professional motives. 72 Virtue ethics emphasize "the nature of the good life for human beings and the character traits that are required for this".…”

Section: Positive Ethicsmentioning

confidence: 99%

Case Study Research in Kenya and South Korea: Reflexivity and Ethical Dilemmas

Nissen

2022

SSRN Journal

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Section: Positive Ethicsmentioning

confidence: 99%

Case Study Research in Kenya and South Korea: Reflexivity and Ethical Dilemmas

Nissen

2022

SSRN Journal

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“…Attempts to use this rationale in the management of thyrotoxic pregnant patients have not been uniformaly successful. Usually the enlargement of the thyroid gland produced by ma ternal antithyroid administration regresses spontaneously after birth and no therapy is needed, unless mechanical airway obstruction occurs (68). It is reasonable to assume that any drug which depresses the synthesis of thyroid hormone and crosses the placenta can produce fetal goiter.…”

Section: Fet Al Pharmacologymentioning

confidence: 99%

Some Aspects of Perinatal Pharmacology

Yaffe¹

1966

Annu. Rev. Med.

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The perinatal period extends from the completion of embryonic dif ferentiation into recognizable anatomic organ structures to the end of the first month of postnatal extrauterine existence. As such it encompasses the most rapid rate of growth and development with accompanying biochemical and physiological changes noted during the total lifespan of the mammalian organism (1).The effects of pharmacologically active agents when administered during this critical period have attracted considerable notoriety in scientific, governmental , industrial, and public circl es because of a number of recent therapeutic misadventures associated with their use. The vulnerability of the developing fetus and newborn infant to chemical agents prescribed on the basis of investigations conducted in adult subjects has been repeatedly demonstrated. The response elicited on the part of the perinatal subject has often been qualitatively and quantitatively dissimilar to that seen in the more mature subject. It is the purpose of this paper to discuss selected aspects of perinatal pharmacology which contribute to our understanding of drug action during this critical period of development. This represents but one aspect of the recently recognized discipline of developmental pharmacology which, in its broadest sense, includes the influence of aging (and the maturational status of the organism) on pharmacologic responses as well as the converse effects of drugs upon maturation and development. Done (2) has recently published a comprehensive review emphasizing these principles as they relate to the neonatal period. THE ROLE OF THE PLACENTAIt is logical to subdivide perinatal pharmacology into prenatal (fetal) and postnatal events. Apart from the recent experimental introduction of blood transfusions directly into the peritoneal cavity of the fetus (3a, 3b), all chemical agents which effect the fetus must traverse the placenta or fetal membranes after maternal administration.The fact that substances may reach the fetus by routes other than the placenta has been shown in many species. In the guinea pig and rabbit, Brambell (4) has demonstrated that antibodies may be transferred

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Management of goiter in children

Schlicke¹,

Berghan²

1958

The American Journal of Surgery

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Suffocative Goiter in the Newborn

Cited by 7 publications

References 3 publications

Case Study Research in Kenya and South Korea: Reflexivity and Ethical Dilemmas

Case Study Research in Kenya and South Korea: Reflexivity and Ethical Dilemmas

Some Aspects of Perinatal Pharmacology

Management of goiter in children

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