Sufentanil added to hyperbaric bupivacaine for subarachnoid block in Caesarean section

Abstract

The addition of sufentanil 5.0 and 7.5 microg to hyperbaric bupivacaine provided adequate anaesthesia for Caesarean section and good postoperative analgesia. Pruritus was the most common side-effect and had a significantly higher incidence when a dose of sufentanil 7.5 microg was used.

Comparison of clinical effects according to the dosage of sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section

“…Braga et al [19] reported that the analgesia duration was lengthened significantly for groups that used 5 µg and 7.5 µg of sufentanil compared to control or 2.5 µg of sufentanil group, and Demiraran et al [7] reported a similar result as our study, showing a significantly longer analgesic duration for groups that used 1.5 µg, 2.5 µg, and 5.0 µg of sufentanil than that of control group. The present study showed that effective analgesic duration, measured using PCA connecting time, was 218.5 ± 71.8 minutes for 2.5 µg sufentanil, 282.3 ± 110.9 minutes for 5 µg.…”

“…Braga et al [19] reports the higher sedation frequencies in patients with increasing sufentanil dosages and although the present study confirms the significant increase in the sedation with increasing sufentanil dosage, there was no excessive sedation in any patient who did not wake at light arousal. In the present study, although nausea was significantly more frequent in groups that used sufentanil, there was no significant difference between Group 2 and 3.…”

“…Wong et al [18] reported that more than an addition of 7.5 µg sufentanil revealed more severe pruritus, and a study by Braga et al [19] revealed that the incidence of pruritus increases as the dosage of the added sufentanil increases. Dahlgren et al [10] reported that when a fixed amount (12.5 mg) of 0.5% hyperbaric bupivacaine with 5.0 µg or 2.5 µg of sufentanil was administered to compare, there was no significant difference in the duration of analgesia, but the pruritus was more frequent when 5 µg was used.…”

Comparison of fentanyl and sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section

“…The duration of effective analgesia is improved by the addition of sufentanil 5.0 and 7.5 µg according to Braga Ade et al [18] and it is effectively prolonged by the addition of sufentanil 1.5, 2.5 and 5.0 µg. Comparison of fentanyl and sufentanil [2] demonstrated that the duration of effective analgesia was significantly increased in the sufentanil 2.5 and 5.0 µg groups in contrast with that of the control group and the fentanyl 10 µg group.…”

Case Report and Mini Literature Review: Anesthetic Management for Severe Peripartum Cardiomyopathy Complicated with Preeclampsia Using Sufetanil in Combined Spinal Epidural Anesthesia

“…We used a slightly higher dosage of intrathecal sufentanil to reduce local anaesthetic requirement and to provide prolonged analgesia, and our patient did not require any epidural top-ups during the surgery 70. This may be advantageous as compared to the use of intrathecal fentanyl, where frequent top ups were required 26,42.…”