Sudden Hip Pain in a Young Woman

Cyrańska-Chyrek, Ewa; Szczepanek‐Parulska, Ewelina; Markuszewski, Jacek; Kruczyński, Jacek; Ruchała, Marek

doi:10.1016/j.amjmed.2017.05.004

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…Although there is no particular threshold of size, the sensitivity of MIBI increases the PA size [ 9 ], which is consistent with our findings. PTHw has lower diagnostic potential in cases of multifocal PA or parathyroid hyperplasia (i.e., in case of MEN syndrome), as PA may mimic thyroid lesions or lymph nodes [ 10 , 11 ]. In our group, PTHw usefulness is also limited in patients with concomitant nodular goitre and/or AITD, in case of higher PTHs values (due to a falsely low PTHw/PTHs ratio) and chronic kidney disease (decreased eGFR).…”

Section: Discussionmentioning

confidence: 99%

Clinical, Biochemical, and Sonographic Factors Influencing Performance of Parathormone Washout Measurement vs. 99mTc-MIBI Scintigraphy in the Preoperative Diagnostics of Parathyroid Adenomas

Szczepanek‐Parulska

Filipowicz

Czepczyński

et al. 2023

JCM

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The purpose of the study was to assess the clinical, biochemical, and sonographic factors influencing the performance of parathormone washout measurement (PTHw) vs. MIBI in the preoperative localization of parathyroid adenoma (PA). The studied group consisted of 39 patients with primary or tertiary hyperparathyroidism. The measurement of PTH concentrations was performed using an electro-chemiluminescence immunoassay. Scintigraphic localization of PA was carried out using dual-tracer planar neck scintigraphy, using 74 MBq 99mTc-pertechnetate and 740 MBq of 99mTc-MIBI. MIBI was unambiguously positive in 74% of patients. Among patients with negative or inconclusive MIBI, 90% had a positive PTHw result. Among patients with negative PTHw, two out of three had a positive MIBI result. The PTHw of lesions <10 mm in their largest diameter yielded positive results in 95%, compared to 75% for MIBI. For lesions ≥10 mm in largest diameter, 88% were visualised using MIBI. In conclusion, PTHw is a highly effective, easy, quick, safe, and relatively cheap procedure which might be considered for PA localisation, especially in patients with lesions presenting typical ultrasound features and a size below 10 mm. MIBI remains a useful procedure in specialized centres, particularly for patients in whom PTHw failed, larger lesions, and in cases of the ectopic location of PA.

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Section: Discussionmentioning

confidence: 99%

Clinical, Biochemical, and Sonographic Factors Influencing Performance of Parathormone Washout Measurement vs. 99mTc-MIBI Scintigraphy in the Preoperative Diagnostics of Parathyroid Adenomas

Szczepanek‐Parulska

Filipowicz

Czepczyński

et al. 2023

JCM

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“…Pagetic lesions may be more easily detected by bone scintigraphy than conventional radiology, due to its higher sensitivity. Paget disease diagnosis is made by exclusion, taking into consideration vitamin D deficiency, hyperparathyroidism, hyperthyroidism, renal osteodystrophy, malignancy, fibrous dysplasia, chronic osteomyelitis, and bone metastases [3,5].…”

Section: Discussionmentioning

confidence: 99%

An adult female with headache and bilateral shank ache

Cyrańska-Chyrek

Szczepanek‐Parulska

Ostałowska

et al. 2019

Endokrynologia Polska

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“…Another frequent endocrine disease that poses both a diagnostic and therapeutic challenge is primary hyperparathyroidism (PHP) [10][11][12]. It is diagnosed most frequently in women during the perimenopausal age, while male patients are affected four times less frequently [13].…”

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confidence: 99%