Sudden Death in Young Adults

Eckart, Robert E.; Shry, Eric A.; Burke, Allen; McNear, Jennifer A.; Appel, David A.; Castillo-Rojas, Laudino M.; Avedissian, Lena; Pearse, Lisa; Potter, Robert N.; Tremaine, Ladd; Gentlesk, Philip J.; Huffer, Linda; Reich, Stephen; Stevenson, William G.

doi:10.1016/j.jacc.2011.01.049

Cited by 332 publications

(91 citation statements)

References 42 publications

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“…10 The numbers are higher in the King County (Washington) Cardiac Arrest Database, being 2.1 for infants of 0-2 years, 0.61 for children aged 3-13 years, 1.44 for young people aged 14-24 years and 4.4 for 25-35-year-olds, respectively. 11 In the Oregon Sudden Unexpected Death Study, the annual incidence of sudden cardiac arrest among blacks was more than twofold higher than in whites for both men and women.…”

Section: Department Of Defense Cardiovascular Death Registry In the Umentioning

confidence: 96%

“…10 Female survivors of cardiac arrest are less likely to have underlying CAD (45 %); valve disease and dilated or arrhythmogenic cardiomyopathy are more common. 23 Following acute myocardial infarction there is increased risk of SCD during the first months due to tachyarrhythmias or other complications such as re-infarction or myocardial rupture, 24 and myocardial scar predisposes to monomorphic ventricular tachycardia (VT).…”

Section: Department Of Defense Cardiovascular Death Registry In the Umentioning

confidence: 99%

“…11 In 5-20 % of cases no significant cardiac abnormality is found at autopsy. 10,47 In a recent Danish registry report on individuals aged <50 years, sudden death was caused by noncardiac diseases, such as pulmonary embolism, meningitis and cerebrovascular bleeding, in 28 % of cases. 48 In sports-related sudden death in the general population, a clear diagnosis is made in <25 % of cases, but the cause is usually an acute coronary syndrome (75 %).…”

Section: Department Of Defense Cardiovascular Death Registry In the Umentioning

confidence: 99%

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A Clinical Perspective on Sudden Cardiac Death

2016

Arrhythmia &Amp; Electrophysiology Review

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This article presents the epidemiology, aetiology and pathophysiology of sudden cardiac death. The modern management of survivors as well as of family members of victims is discussed, as are the relevant recommendations of guidelines prepared by learned societies. KeywordsOut-of-hospital cardiac arrest, sports-related sudden death, sudden cardiac death, sudden unexplained death syndrome Disclosure: The authors have no conflicts of interest to declare.

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Section: Department Of Defense Cardiovascular Death Registry In the Umentioning

confidence: 96%

Section: Department Of Defense Cardiovascular Death Registry In the Umentioning

confidence: 99%

Section: Department Of Defense Cardiovascular Death Registry In the Umentioning

confidence: 99%

See 1 more Smart Citation

A Clinical Perspective on Sudden Cardiac Death

2016

Arrhythmia &Amp; Electrophysiology Review

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“…Arrhythmias and ischemic heart disease comprise a significant percentage of sudden cardiac death especially in the older population [1] [2]. Patients with ischemic heart disease presenting with ventricular arrhythmias (VA) represent a high risk population compared to the rest of the patients undergoing surgical revascularisation [3].…”

Section: Introductionmentioning

confidence: 99%

Coronary Artery Bypass Surgery for Patients Presenting with Ventricular Arrhythmias: Propensity Matched Early and Late Outcome

Habib¹,

Hussain²,

Jarvis³

et al. 2018

WJCS

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Objectives: Patients with ischemic ventricular arrhythmia (IVA) in the form of fibrillation or tachycardia represent a surgical challenge. Evidence in the literature suggests that ventricular arrhythmia threatens survival even after cardiac surgery. We aim to review the results of our patients presenting with IVA with regard to short and long term outcome following cardiac surgery. Methods: This was a retrospective study of data entered prospectively into our cardiac surgical database between January 1999 and September 2015. A total of 9609 patients underwent Cardiac Surgery which included 54 patients after surviving IVA. The short-and long-term outcomes were compared to a propensity matched group. Actuarial survival was calculated using Kaplan Meier analysis. Results: The 54 study group patients were propensity matched on a 1:2 basis with a control group of non-IVA (n = 108). The baseline preoperative characteristics and risk factors were similar between the 2 groups and all cases underwent CABG only. Univariate analysis showed pacing postoperatively (33.3 vs 66.7%; p = 0.001) and postoperative ventricular arrhythmia (10 vs 22.2%; p = 0.039) to be significantly higher in the IVA group. Cox-multivariate analysis showed postoperative ventricular arrhythmia in either group (Hazard ratio = 1.5) to be the only significant factor to impact mortality (p < 0.001). Long term survival was not significantly different between the two groups (10.4; CI: 9.08 -11.75 vs 9.3; CI: 7.61 -11.01 yrs, p = 0.3). Conclusion: Cardiac surgery on patients presenting with IVA can be performed safely yielding short and long term results equivalent to non-IVA cases. These patients should not be denied surgery with consideration of good long term outcome.

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“…10 SCD is more frequent in male subjects, and its frequency increases with age, mainly due to a higher prevalence of coronary artery disease and to the physiological aging process of the myocardium. 11 The etiology of SCD is variable among age groups, as in younger patients there is a predominance of cardiomyopathies and channelopathies, myocarditis and recreational drug misuse, while in older subjects there is a shift towards degenerative disease, coronary artery disease, valvular disorders, and congestive heart failure.…”

Section: Introductionmentioning

confidence: 99%