Sudden Cardiac Death Risk Stratification of the Early Repolarization Syndrome: An Updated Review of the Literature

El-Azrak, Mohammed; Darar, Charmake; Boutaybi, Mohammed; Ouafi, Noha El; Bazid, Zakaria

doi:10.1007/s11886-023-01842-5

Cited by 1 publication

(2 citation statements)

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“…This finding suggests that ventricular depolarization is unlikely to contribute to arrhythmogenesis in individuals with ERP. However, it should be noted that in large-scale studies, QRS duration was identical in individuals with and without ERP [2,3,7].…”

Section: Discussionmentioning

confidence: 87%

“…The early repolarization pattern (ERP) refers to the presence of a notch-or slur-like abnormality observable on an electrocardiogram (ECG) at the end of the QRS complex, also known as the J wave (Figure 1), which is traditionally considered to be a benign phenomenon. However, recent studies have confirmed an association between the ERP and life-threatening ventricular arrhythmias (early repolarization syndrome-ERS), particularly ventricular tachycardia (VT) and ventricular fibrillation (VF) [1,2].…”

Section: Introductionmentioning

confidence: 99%

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Exercise-Induced Electrocardiographic Changes in Healthy Young Males with Early Repolarization Pattern

Kocsis,

Pap,

László

et al. 2024

Diagnostics

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Background: Exercise-induced modifications in ECG parameters among individuals with an early repolarization pattern (ERP) have not been evaluated in detail. We aimed to assess this phenomenon, with potential associations with arrhythmogenesis. Methods: Twenty-three young, healthy males with ERP (ERP+) participated in this study, alongside a control group, which consisted of nineteen healthy males without ERP (ERP−). ECGs at baseline, at peak exercise (Bruce protocol), and during the recovery phase were analyzed and compared between the two groups. Results: The treadmill test demonstrated strong cardiovascular fitness, with similar chronotropic and pressor responses in both groups. In the baseline ECGs, the QRS complex and the QT interval were shorter in the ERP+ group. During exercise, the P-wave duration was significantly longer and the QRS was narrower in the ERP+ group. In the recovery phase, there was a longer P wave and a narrower QRS in the ERP+ group. During the treadmill test, the J wave disappeared or did not meet the criteria required for ERP diagnosis. Conclusions: The slowed intra-atrial conduction found during exercise could be predictive of atrial arrhythmogenesis in the setting of ERP. The disappearing of J waves during exercise, due to increased sympathetic activity, has potential clinical significance.

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Section: Discussionmentioning

confidence: 87%

Section: Introductionmentioning

confidence: 99%