Sudden Cardiac Death as First Manifestation of Heart Disease in Women

Reinier, Kyndaron; Stecker, Eric C.; Uy‐Evanado, Audrey; Chugh, Harpriya; Binz, Andrea; Nakamura, Kotoka; Sargsyan, Arayik; Jui, Jonathan; Chugh, Sumeet S.

doi:10.1161/circulationaha.119.044169

Cited by 8 publications

(3 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In an American retrospective analysis of mortality after sudden cardiac arrest, left ventricular ejection fraction <40% and CAD were the most powerful predictors of mortality among male and female patients, respectively 9. Multiple studies have found sudden cardiac arrest and SCD more common in females without prior CAD or left ventricle dysfunction,7 10 28 underlining the need for further research into sex-specific cardiac pathophysiology among females. In addition, gender differences in cultural, psychosocial, behavioural and socioeconomic factors also affect the risk of SCD among male and female population 29.…”

Section: Discussionmentioning

confidence: 99%

Sex differences in sudden cardiac death in a nationwide study of 54 028 deaths

Skjelbred

Rajan

Svane

et al. 2022

Heart

View full text Add to dashboard Cite

ObjectiveSudden cardiac death (SCD) is a leading cause of death and is more common among males than females. Epidemiological studies of sex differences in SCD cases of all ages are sparse. The aim of this study was to examine differences in incidence rates, clinical characteristics, comorbidities and autopsy findings between male and female SCD cases.MethodsAll deaths in Denmark in 2010 (54 028) were reviewed. Autopsy reports, death certificates, discharge summaries and nationwide health registries were reviewed to identify cases of SCD. Based on the available information, all deaths were subcategorised into definite, probable and possible SCD.ResultsA total of 6867 SCD cases were identified, of which 3859 (56%) were males and 3008 (44%) were females. Incidence rates increased with age and were higher for male population across all age groups in the adult population. Average age at time of SCD was 71 years among males compared with 79 among females (p<0.01). The greatest difference in SCD incidence between males and females was found among the 35–50 years group with an incidence rate ratio of 3.7 (95% CI: 2.8 to 4.8). Compared with female SCD victims, male SCD victims more often had cardiovascular diseases and diabetes mellitus (p<0.01).ConclusionThis is the first nationwide study of sex differences in SCD across all ages. Differences in incidence rates between males and females were greatest among young adults and the middle-aged. Incidence rates of SCD among older female population approached that of the male population, despite having significantly more cardiovascular disease and diabetes in male SCD cases.

show abstract

Section: Discussionmentioning

confidence: 99%

Sex differences in sudden cardiac death in a nationwide study of 54 028 deaths

Skjelbred

Rajan

Svane

et al. 2022

Heart

View full text Add to dashboard Cite

show abstract

“…Although known previous heart diseases confer a higher risk of SCD, the vast majority of SCDs occur in the general population with approximately only half of the cases with heart disease diagnosed before the event. 16 , 17 The annual incidence is estimated between 30 and 125 per 100.000 person-years with an exponential increase over age and higher incidence among men as compared with women ( Figure 3 ). 2 , 17 Despite relatively low incidence, the absolute number of cases worldwide is high and estimated to be 6–9 million yearly from extrapolation of the annual number of deaths in the world.…”

Section: Sudden Cardiac Death Prediction In the General Populationmentioning

confidence: 99%

Risk stratification of sudden cardiac death: a review

Tfelt-Hansen,

Garcia,

Albert

et al. 2023

Europace

View full text Add to dashboard Cite

Sudden cardiac death (SCD) is responsible for several millions of deaths every year and remains a major health problem. To reduce this burden, diagnosing and identification of high-risk individuals and disease-specific risk stratification are essential. Treatment strategies include treatment of the underlying disease with lifestyle advice and drugs and decisions to implant a primary prevention implantable cardioverter-defibrillator (ICD) and perform ablation of the ventricles and novel treatment modalities such as left cardiac sympathetic denervation in rare specific primary electric diseases such as long QT syndrome and catecholaminergic polymorphic ventricular tachycardia. This review summarizes the current knowledge on SCD risk according to underlying heart disease and discusses the future of SCD prevention.

show abstract

“…[ 51 52 53 ] However out of hospital cardiac arrest was increased during COVID-19 outbreak in Italy which has been corelated with COVID-19 outbreak. [ 54 55 ]…”

Section: Acute Coronary Syndromementioning

confidence: 99%

Covid 19 and its cardiovascular effects

Rastogi

Tewari

2020

Ann Card Anaesth

View full text Add to dashboard Cite

COVID-19 pandemic is mainly related with the pulmonary problems initially but now as the pandemic is growing it is observed that almost all organ systems of the body are affected. Up to 20-30% patients who are admitted in Covid hospitals are showing cardiovascular involvement. Severity of cardiovascular disease in a COVID-19 patient depends whether a patient is having pre-existing cardiac disease or not. Patients with pre-existing cardiac disease have more severe infection and associated mortality. Severe COVID-19 infection shows close association with myocardial damage and various arrythmias. The cardiovascular involvement occurs by either engagement directly with the angiotensin converting enzyme 2 or indirectly by the effect of inflammatory mediators which are generated as a result of viral-host response to infection. The COVID-19 disease is said to produce a wide spectrum of affliction ranging between even asymptomatic patient to Cardiovascular syndrome. Even after recovering from COVID-19 patients can reappear in the hospital with cardiomyopathies and arrythmias.

show abstract

Sudden Cardiac Death as First Manifestation of Heart Disease in Women

Cited by 8 publications

References 4 publications

Sex differences in sudden cardiac death in a nationwide study of 54 028 deaths

Sex differences in sudden cardiac death in a nationwide study of 54 028 deaths

Risk stratification of sudden cardiac death: a review

Covid 19 and its cardiovascular effects

Contact Info

Product

Resources

About