Sucrose Solubility in Binary Liquid Mixtures Formed by Water–Methanol, Water–Ethanol, and Methanol–Ethanol at 303 and 313 K

Abstract

This work presents a study of solid–liquid equilibrium of sucrose in three different binary liquid mixtures, methanol–ethanol, methanol–water, and ethanol–water for the temperatures of 303 and 313 K covering the whole composition range of the binary liquid solution. The data are presented as a function of the dielectric constant of the binary liquid mixture taking into account the self-association of water and alcohol. From a dissolution phenomenon standpoint, it seems that the temperature is more important than the dielectric constant of the binary liquid solution for the solubility mechanism. For each temperature, it was observed that the sucrose solubility is directly proportional to the dielectric constant of the binary liquid mixture.

Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K

“…2,3 In this way, some physicochemical properties of this agent in aqueous cosolvent mixtures, like solubility and volumetric contributions, are very important to facilitate the duties of pharmaceutical scientist during dosage forms design duties. 4 Although sucrose has been used for centuries in several industries, and several reports about its solubility in solvent mixtures have been presented in the literature, [5][6][7][8] the physicochemical information about their mixed aqueous solutions is still far to be complete. 4 In particular, at the best of our knowledge, no solubility values of sucrose in aqueous polyethylene glycol (PEG) mixtures have been reported in the literature.…”

Modeling Phase Equilibrium of Common Sugars Glucose, Fructose, and Sucrose in Mixed Solvents

“…Solubility of sucrose in various mass fraction water-EtOH solutions, including both the () NRTL and () aNRTL model, and data from (●) Young and Jones, (■) Abed et al, (Δ) Galvao et al, (◊) Peres and Macedo, and (□) Gong et al …”

“…Solubility of sucrose in (a) water-MeOH and (b) MeOH-EtOH solutions, including the () NRTL and () aNRTL model and data from (◯) Macedo and Peres, and (□) Galvao et al w s is mass fraction in the solute-free solution.…”

“…Mutual solubility of (a) glucose+sucrose and (b) fructose+sucrose, including the () NRTL and () aNRTL models and data from (◯) Abed et al, (□) Kelly, (◊) Young et al, − (▲) Galvao et al, (▲) Jackson and Silsbee, and (●) Alavi et al …”

“…Many researchers have proposed activity or osmotic coefficient models for sugars dissolved in water and other solvents. Several sources used their own empirical models, usually in the form of a polynomial series. − These can be very accurate but tend to fit only the data from which they are derived and are not easily applicable to other conditions or systems. The most common models used are UNIFAC and its derivatives − and UNIQUAC and its derivatives. ,,− These models tend to be accurate, although those with better fits − ,− introduce modifications to the original UNIFAC and UNIQUAC models for which there may not be parameters available for extensions to other systems.…”