???Sucrose Analgesia??? and Diphtheria-Tetanus-Pertussis Immunizations at 2 and 4 Months

Sweet Solution Analgesia

“…Same had been noticed for other routinely applied procedures such as intravenous or arterial line insertion, lumbar puncture, tape removal and venipuncture [37][38][39]. This analgesic efect also extends to even older infants; sucrose was also efective in lowering pain scores due to immunization for babies aged between 1 and 12 months [23,40]. Sucrose was beneicial when paired with other analgesic for pain relief during circumcision, probably since circumcision is a more intensely painful procedure than other routine procedures undertaken at NICU, yet it gave a synergistic efect with other analgesic methods [41].…”

Effectiveness of sucrose analgesia in newborns undergoing painful medical procedures

“…12 Sucrose may be a relatively weak analgesic 28 that is more effective at calming infants during the recovery period after a painful procedure than during the actual procedure when pain is at its peak. 29 Finally, we used a fully retractable automatic lancet during the heel-lances and collected only a single drop of blood. This resulted in minimal pain in newborns, 18 which was perhaps too low for sucrose to have a measurable effect.…”

Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline

“…Eleven trials with a total of 1452 infants and children 17,[23][24][25][26][27][28][29][30][31][32] were included in the systematic review. 12 A meta-analysis of data from six trials involving single or multiple vaccine injections (n = 665 infants up to 12 months of age) 17,[26][27][28]31,32 showed that sucrose solution with or without non-nutritive sucking reduced acute pain.…”