Succinic acid production from whey and lactose by Actinobacillus succinogenes 130Z in batch fermentation

Louaste, Bouchra; Eloutassi, Noureddine

doi:10.1016/j.btre.2020.e00481

Cited by 26 publications

(18 citation statements)

References 28 publications

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“…Agro-industrial residues as lignocellulosic, agricultural residues and dairy residues are characterized by their high availability and advantageous composition. These residues are a potential source of hexoses, pentoses, glycerol, starch, oligomers and lactose (Cizeikiene et al 2018;Serna-Loaiza et al 2019;Louasté and Eloutassi 2020;Omwene et al 2020).…”

Section: Challenges Raised By the Use Of Alternative Feedstocksmentioning

confidence: 99%

From the culture broth to the erythritol crystals: an opportunity for circular economy

Daza-Serna

Serna-Loaiza

Masi

et al. 2021

Appl Microbiol Biotechnol

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The reduction of sugar intake by adults has been stated by the World Health Organization as an important strategy to reduce the risk of non-communicable diseases. Erythritol is a four-carbon sugar alcohol that is considered as a highly suitable substitution for sucrose. This review article covers approaches for the separate stages of the biotechnological production of erythritol from cultivation to the downstream section. The first part focuses on the cultivation stage and compares the yields of erythritol and arising by-products achieved with different types of substrates (commercial versus alternative ones). The reported numbers obtained with the most prominently used microorganisms in different cultivation methods (batch, fed-batch or continuous) are presented. The second part focuses on the downstream section and covers the applied technologies for cell removal, recovery, purification and concentration of erythritol crystals, namely centrifugation, membrane separation, ion and preparative chromatography, crystallization and drying. The final composition of the culture broth and the preparative chromatography separation performance were identified as critical points in the production of a high-purity erythritol fraction with a minimum amount of losses. During the review, the challenges for a biotechnological production of erythritol in a circular economy context are discussed, in particular regarding the usage of sustainable resources and minimizing waste streams. Key points • Substitution of sucrose by erythritol can be a step towards a healthier society • Biotechnological production of erythritol should follow a circular economy concept • Culture broth composition and preparative chromatography are keys for downstreaming • Substrate, mother liquor and nutrients are challenges for circular economy

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Section: Challenges Raised By the Use Of Alternative Feedstocksmentioning

confidence: 99%

From the culture broth to the erythritol crystals: an opportunity for circular economy

Daza-Serna

Serna-Loaiza

Masi

et al. 2021

Appl Microbiol Biotechnol

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“…A beneficial shift in their production strategies using renewable feedstocks (eco-friendly) may compete with energy-intensive processes using petroleum based feedstocks (Werpy and Petersen 2004;Saxena et al 2017). Succinic acid is a high potential candidate as a building block chemical and intermediary for many other chemicals made from renewable resources (Stichnothe et al 2020;Louasté and Eloutassi 2020).…”

Section: Succinic Acid: Case Studymentioning

confidence: 99%

Platform molecule from sustainable raw materials; case study succinic acid

Salma

Djelal

Abdallah

et al. 2021

Braz. J. Chem. Eng.

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Platform molecules were defined by the US Department of Energy, as bio-based or bio-derived chemicals whose constituting elements totally originated from biomass and could be used as building blocks for the production of commodity and refined chemicals. These chemicals can subsequently be converted into a number of high-value bio-based chemicals or materials.Today, there is a growing urge for the discovering of a cheaper and cleaner way for the environment to produce platform molecules from renewable substrate such as carbon. Succinic acid (SA) is considered as a key platform chemical since it is used as a precursor for other valuable chemicals and has aroused interest worldwide with its wide applications. This review aims at highlighting the currently available information about the mechanisms involved in the production of platform molecules, especially the SA production. In this review, the processing technologies used in the production of platform molecules are described, in addition to the information regarding the optimization of key parameters, the mechanisms of genetic engineering and finally the redox potential and purification processes which are known as alternative cost-competitive providers of fossil fuels.

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“…Most of the commercial succinic acid production is done by chemical technologies like catalytic hydrogenation or electrolytic reduction of maleic anhydride. In the last years, it was found that it can be produced using CW and lactose as substrates by Actinobacillus succinogenes 130Z in a batch fermentation [64].…”

Section: Organic Acidsmentioning

confidence: 99%

Value-Added Compounds with Health Benefits Produced from Cheese Whey Lactose

Guevara-Alvarado¹,

Gutiérrez‐Méndez²,

Carrillo-Pérez³

et al. 2020

Lactose and Lactose Derivatives

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Cheese whey (CW) is the yellow-green liquid main by-product from cheese manufacturing. Historically, it has been recognized as a major environmental pollutant. Nowadays, it represents a source of high-quality nutrients, such as lactose. Enzymatic bioprocesses, chemical synthetic reactions and microbial bioprocesses use lactose as substrate to obtain relevant derivatives such as lactitol, lactulose, lactosucrose, sialyllactose, kefiran and galacto-oligosaccharides. These lactose derivatives stimulate the growth of indigenous bifidobacteria and lactobacilli improving the intestinal motility, enhancing immunity and promoting the synthesis of vitamins. Also, they have versatile applications in pharmaceutical, biotechnological and food industries. Therefore, this book chapter shows the state of the art focusing on recent uses of CW lactose to produce value-added functional compounds and discusses new insights associated with their human health-promoting effects and well-being.

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Succinic acid production from whey and lactose by Actinobacillus succinogenes 130Z in batch fermentation

Cited by 26 publications

References 28 publications

From the culture broth to the erythritol crystals: an opportunity for circular economy

From the culture broth to the erythritol crystals: an opportunity for circular economy

Platform molecule from sustainable raw materials; case study succinic acid

Value-Added Compounds with Health Benefits Produced from Cheese Whey Lactose

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