Succinct and Expeditious Synthesis of Cu₂O Nanoparticles by Using Liquid Jaggery: Anticancer and Wound Healing Activity Analyses

Abstract

Nanotechnology has expanded substantially over the last several decades as an aftermath of its ubiquitous prevalence in scientific research and technology. The current study demonstrates the ecologically benign production of novel nanoparticles comprised of copper oxide (Cu2O NPs). Liquid jaggery played an eloquent role in the present endeavour perpetrating both as a reducing and capping agent. Energy‐Dispersive X‐ray spectroscopy (EDX), UV‐Visible Spectroscopy, Field emission‐scanning electron microscopy (FESEM), Fourier Transform Infrared (FTIR) spectroscopy, X‐ray diffraction (XRD) studies, Particle size and Zeta potential supported successful synthesis of Cu2O NPs. This study enumerated and assessed the cytotoxicity of Cu2O NPs on three cancer cell lines: HeLa (cervical cancer), MCF‐7 (breast cancer), and MDAMB‐231 (triple negative breast cancer). IC50 (μg/mL) for Cu2O NPs was recorded as 51.24, 59.24, 64.80 for HeLa, MCF‐7 and MDAMB‐231 cells respectively. The Cu2O NPs also exhibited excellent wound healing efficacy, increased cellular mobility including an elevated rate of closure of wounds (93.70 %).