Successful Use of Autologous Fibrin Gel in Traumatic Bronchopleural Fistuala

Nicholas, Jeffery M.; Dulchavsky, Scott A.

doi:10.1097/00005373-199201000-00018

Cited by 15 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This preparation is usually used in cardiac, thoracic, and maxillofacial surgery, mainly in adults 10,11 . When used in adults with bronchopleural fistulae, fibrin glue pleurodesis has rapidly resolved air leaks in most cases, and these leaks are usually sealed within 24 h after pleurodesis 12 …”

Section: Discussionmentioning

confidence: 99%

Use of fibrin glue in the treatment of pneumothorax in premature infant

Nishizaki

Suganuma

Nagata

et al. 2012

Pediatrics International

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Use of fibrin glue in the treatment of pneumothorax in premature infant

Nishizaki

Suganuma

Nagata

et al. 2012

Pediatrics International

View full text Add to dashboard Cite

“…Thoracic Surgery Several beneficial effects have been described in clinics with the application of fibrin sealant preparations: reduc tion in air or fluid leakage from pulmonary parenchymal staple lines, reenforcement of esophageal anastomoses, closing of bronchopleural fistulas (especially those less than 4 mm in diameter), using a fiberoptic flexible broncho scope, and treatment of pneumothorax using video-assisted surgical techniques. It has also been used for closure of trachoesophageal [46] and bronchopleural [47,48] fistulae by fiberoptic bronchoscopie application. The efficacy of fibrin sealant, in comparison with sutures alone, for avoiding bronchial and alveolar leakages after pulmonary resections was demonstrated in a prospective and randomized clinical trial [49].…”

Section: Main Clinical Applicationsmentioning

confidence: 99%

Fibrin Sealant: Scientific Rationale, Production Methods, Properties, and Current Clinical Use

Radosevich¹,

Goubran²,

Burnouf³

1997

Vox Sanguinis

191

127

View full text Add to dashboard Cite

Fibrin sealant is a complex plasma-derived product which is increasingly used as a biodegradable tissue adhesive or sealant to stop or control bleeding or provide air and fluid tightness in many surgical situations. This review describes the historical development of current fibrin sealant preparations and the scientific rationale behind the alleged physiological benefits of its major plasma-derived components. A comparison in the extraction methods and viral reduction treatments applied to current commercial products and autologous preparations, and their respective advantages and limits, are discussed. Application devices used for surgical applications are described. A survey of the major clinical applications in various surgical areas is presented. Current issues in terms of viral safety, definition of optimal fibrin sealant composition, and regulatory concerns, especially to demonstrate clinical efficacy, are also included.

show abstract

“…Various bronchoscopic attempts to treat PAL have been many and include endovascular metallic coils, [ 5 ] glues, [ 6 ] spigots, [ 7 ] stents, [ 8 ] silver nitrate, [ 9 ] and gel foam. [ 10 ] But none of these methods has shown significant efficacy to replace surgical intervention in the treatment of PAL. One-way EBV placement, initially developed as a nonsurgical method of lung volume reduction for emphysema, has provided a new tool for use in the closure of persistent air leak.…”

Section: Discussionmentioning

confidence: 99%

Bronchoscopic valve placement for the treatment of persistent air leaks

Huang

Ding²,

Xu³

2018

Medicine

View full text Add to dashboard Cite

Persistent air leaks (PALs) are associated with increased morbidity, prolonged hospital stay, and increased treatment costs. Endobronchial 1-way valves have been recently used as a potential less invasive treatment option. We sought to investigate the effects of valve therapy in treating this condition. The patients with evidence of continuous air leak flow whose chest tubes remained in place for more than 7 days were treated with bronchoscopic closure using 1-way valves. The source of the air leak was identified by the Chartis system.A total of 11 patients (1 woman, 10 men; mean age, 68 years) who underwent valve placement were eligible to be enrolled from January 2015 through January 2017. Six patients had postoperative PAL, and 5 had a secondary spontaneous pneumothorax. The number of used valves varied from 1 to 3 (median 1). The resolution of the leak was complete in 8 patients (72.7%), whose mean duration of air leak before and after valve deployment was 58.5 and 4.5 days, respectively. There were no complications related to the valve deployment.Bronchoscopic placement of 1-way valves is a safe procedure that could help manage patients with prolonged PALs. A prospective randomized trial with cost-efficiency analysis is necessary to better define the role of this bronchoscopic intervention and demonstrate its effect on air leak duration.

show abstract

Successful Use of Autologous Fibrin Gel in Traumatic Bronchopleural Fistuala

Cited by 15 publications

References 0 publications

Use of fibrin glue in the treatment of pneumothorax in premature infant

Use of fibrin glue in the treatment of pneumothorax in premature infant

Fibrin Sealant: Scientific Rationale, Production Methods, Properties, and Current Clinical Use

Bronchoscopic valve placement for the treatment of persistent air leaks

Contact Info

Product

Resources

About