Successful Treatment of Steroid-Resistant Fibrosing Organising Pneumonia Causing Respiratory Failure With Mycophenolic Acid

Paul, C. Hébert; Lin-Shaw, Ammy; Joseph, Mariamma; Kwan, Keith; Sergiacomi, Gianluigi; Mura, Marco

doi:10.1016/j.chest.2016.08.290

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2021

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“…In addition, glucocorticoids in nearly one-third of the patients could cause adverse events including gastrointestinal bleeding, arterial hypertension, bone fracture, diabetes mellitus, body-weight increase, and increase mortality rate [ 6 ]. Successful treatment of steroid-resistant COP is reported when, in combination with steroids or alone, rituximab [ 12 ], azathioprine [ 4 , 10 ], cyclophosphamide, cyclosporine A [ 4 ], and mycophenolic acid [ 13 ] are applied [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Case of Severe Treatment-Resistant Cryptogenic Organizing Pneumonia

Grigoravičius

Žurauskas

Gruslys

et al. 2021

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Cryptogenic organizing pneumonia is a rare interstitial lung disease with different onset of symptoms, which responds rapidly to glucocorticoid treatment. We present a case of cryptogenic organizing pneumonia which manifested as a progressive 3-year dyspnea that ultimately has led to acute respiratory failure. Moreover, treatment with prednisone for this patient exhibited slow onset of the effect.

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