Successful treatment of progressive macular hypomelanosis

Abstract

Progressive Macular Hypomelanosis (PMH) is a common but often misdiagnosed disorder of acquired hypopigmentation. An adolescent female presented with irregular, hypopigmented patches ultimately diagnosed as PMH. Complete repigmentation was achieved with narrowband UVB phototherapy, benzoyl peroxide wash, and clindamycin lotion.

Adolescent extra‐truncal progressive macular hypomelanosis

“…4 Successful treatment with topical benzoyl peroxide and clindamycin, known treatments for C. acnes-related acne, provides additional support for this theory. 12,13 The two cases described here did not have a seborrheic distribu-…”

“…Because C. acnes predominantly colonizes pilosebaceous structures in the skin, the typical truncal distribution and prevalence in adolescence is thought to be related to the increased sebum concentration on the trunk of adolescents 4 . Successful treatment with topical benzoyl peroxide and clindamycin, known treatments for C. acnes ‐related acne, provides additional support for this theory 12,13 …”