Successful treatment of knee erythromelalgia with topical oxymetazoline

Abstract

Erythromelalgia is an infrequent syndrome with a profound impact on quality of life. Its management is usually challenging and multiple treatments have been reported with variable response rates. To the best of our knowledge, we present the first case of erythromelalgia successfully treated with topical oxymetazoline.

Topical treatments for erythromelalgia

“…42 In a case study, topical oxymetazoline 1% cream has been shown to reduce the number of attacks of erythromelalgia and improve the quality of life of a 68-year old woman with a 20-year history of erythromelalgia. 43…”

“…These agents target the increased blood flow associated with rosacea, which is also present in erythromelalgia 42 . In a case study, topical oxymetazoline 1% cream has been shown to reduce the number of attacks of erythromelalgia and improve the quality of life of a 68‐year old woman with a 20‐year history of erythromelalgia 43 …”