Successful Treatment ofBacillus cereusBacteremia in a Patient with Propionic Acidemia

Abstract

Bacillus cereus can cause serious, life-threatening, systemic infections in immunocompromised patients. The ability of microorganism to form biofilm on biomedical devices can be responsible for catheter-related bloodstream infections. Other manifestations of severe disease are meningitis, endocarditis, osteomyelitis, and surgical and traumatic wound infections. The most common feature in true bacteremia caused by Bacillus is the presence of an intravascular catheter. Herein, we report a case of catheter-related bacteremia caused by B. cereus in a patient with propionic acidemia.

Comparative Analysis of Bacillus cereus Group Isolates' Resistance Using Disk Diffusion and Broth Microdilution and the Correlation between Antimicrobial Resistance Phenotypes and Genotypes

“…The Centers for Disease Control and Prevention recommend ciprofloxacin, doxycycline, and β-lactam antibiotics for treatment of inhalation exposure to B. anthracis (genomospecies B. mosaicus biovar Anthracis = B. Anthracis ) ( 17 ). Severe non-anthrax Bacillus cereus infections are commonly treated with vancomycin, gentamicin, linezolid, levofloxacin, and clindamycin antibiotics ( 18 – 21 ). These antibiotics are widely used clinically due to the high prevalence of β-lactamases found among Bacillus cereus group isolates ( 22 – 24 ), although specific β-lactams (e.g., carbapenems) are also used in combination for the treatment of clinical cases ( 18 , 25 ).…”

Diagnósticos microbiológicos en un hospital gineco-obstétrico pediátrico: Un reporte de centro único

“…Therefore, the identification of these staphylococci according to species should be a routine practice in every clinical microbiology laboratory, with the aim of establishing preventive measures in pediatric hospitalization areas, the eradication of infectious processes and even their resistance to antimicrobials. On the other hand, it is worth noting that in the microbiological reports considered for this report there was only one culture of Bacillus cereus, identified in nasal aspirate, a finding not reported in the consulted literature; The spores of this gram + bacillus are reported to be abundant in the soil, fresh water, hospital environment and even in the gastrointestinal flora, and can cause acute gastroenteritis and fatal systemic infections in newborns, but it is considered a contaminant when isolated from clinical samples and its the most common characteristic in true bacteremia, given its presence in an intravascular catheter [24].…”

Comparative analysis of Bacillus cereus group isolates’ resistance using disk diffusion and broth microdilution and the correlation between resistance phenotypes and genotypes

“…The Centers for Disease Control and Prevention recommend ciprofloxacin, doxycycline, and beta-lactam antibiotics for treatment of inhalation exposure to B. anthracis (genomospecies B. mosaicus biovar Anthracis = B. Anthracis) (19). Severe non-anthrax Bacillus cereus infections are commonly treated with vancomycin, gentamicin, and clindamycin antibiotics (20)(21)(22)(23). These antibiotics are widely used clinically due to the high prevalence of beta-lactamases found among Bacillus cereus group isolates (24)(25)(26), although specific beta-lactams (e.g., carbapenems) are also used for the treatment of clinical cases in combination (20,27).…”

“…Severe non-anthrax Bacillus cereus infections are commonly treated with vancomycin, gentamicin, and clindamycin antibiotics (20)(21)(22)(23). These antibiotics are widely used clinically due to the high prevalence of beta-lactamases found among Bacillus cereus group isolates (24)(25)(26), although specific beta-lactams (e.g., carbapenems) are also used for the treatment of clinical cases in combination (20,27). Notably, there are reports of poor patient outcomes due to carbapenem resistance (14,28).…”