Successful Treatment of Cytophagic Histiocytic Panniculitis with Modified CHOP-E

Matsue, Kosei; Itoh, Mami; Tsukuda, Koji; Miyazaki, Kazuhiro; Kokubo, Takeshi

doi:10.1097/00000421-199412000-00003

Cited by 18 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Occasionally, it responds to glucocorticosteroids, but some patients may develop severe systemic forms, which can be fatal. 11 Methotrexate, 12 azathioprine, 13,14 antimalarials, 15 thalidomide, 16 cyclophosphamide, 17 polychemotherapy, 4,18 and cyclosporine 19 have been reported in the management of isolated cases with resistant forms.…”

mentioning

confidence: 99%

Long-Term Evolution of Cytophagic Histiocytic Panniculitis

et al. 2010

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

Long-Term Evolution of Cytophagic Histiocytic Panniculitis

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Historically, responses to combination chemotherapy have been reported but are usually of short duration and CRs are rare. 49,50 There are reports of successful allogeneic stem cell transplantation [51][52][53] and prolonged remissions with combination chemotherapy followed by an autologous stem cell transplant. 54 However, the rarity of this disease and the infrequent need for aggressive therapy hampers our understanding of the utility of such approaches.…”

Section: Subcutaneous Panniculitis-like T-cell Lymphomamentioning

confidence: 99%

Zebras and hen's teeth: recognition and management of rare T and NK lymphomas

Mehta‐Shah

Horwitz

2015

Hematology

View full text Add to dashboard Cite

Although all the peripheral T-cell lymphomas are uncommon, there are some entities that are truly rare. Subtypes, such as enteropathy-associated T-cell lymphoma, hepatosplenic T-cell lymphoma, extranodal NK/T-cell lymphoma, and subcutaneous panniculitis-like T-cell lymphoma, have an approximate annual incidence in United States of <500 each. In these very rare subtypes, there is limited data to guide clinical decision-making. As such, our treatment decisions are often based on extrapolation, case series, personal experience, and biases. We summarize the existing data regarding initial management of these entities and compare how that management follows paradigms established for the more common T-cell lymphomas.

show abstract

“…Some authors have suggested aggressive polychemotherapy early on in patients with systemic involvement [5]. Some authors have suggested aggressive polychemotherapy early on in patients with systemic involvement [5].…”

Section: Commentsmentioning

confidence: 99%

Fatal cytophagic histiocytic panniculitis after a short response to cyclosporine

Guitart

Sethi

Gordon

1998

Acad Dermatol Venereol

View full text Add to dashboard Cite

Cytophagic histiocytic panniculitis (CHP) is a disorder characterized by a histiocytic infiltrate in the subcutaneous adipose tissue which often extends to involve systemic organs. Fever, pancytopenia, hepatosplenomegaly, mucosal ulcers and serositis are common systemic symptoms. Although remissions have been reported, the disease tends to follow a chronic course often complicated by terminal hemorrhagic diathesis and death. Several reports in the recent literature have suggested that cyclosporine is the treatment of choice in CHP. We report the first case of cyclosporine treatment failure in CPH. Despite an initial response to treatment and persistent resolution of cutaneous lesions, the internal disease progressed resulting in the patient's death. Therefore the evolution of skin lesions and signs of systemic involvement may not be an accurate assessment of disease activity in patients with CHP being treated with cyclosporine.

show abstract

Successful Treatment of Cytophagic Histiocytic Panniculitis with Modified CHOP-E

Cited by 18 publications

References 0 publications

Long-Term Evolution of Cytophagic Histiocytic Panniculitis

Long-Term Evolution of Cytophagic Histiocytic Panniculitis

Zebras and hen's teeth: recognition and management of rare T and NK lymphomas

Fatal cytophagic histiocytic panniculitis after a short response to cyclosporine

Contact Info

Product

Resources

About