Successful treatment of cystoid macular edema with valdecoxib

Abstract

The fast and persistent control of macular edema with valdecoxib warrants further investigation.

Successful treatment of pseudophakic cystoid macular edema with intravitreal bevacizumab

“…4 Prompt treatment on recognition of the complication is warranted; if macular edema has been present for several months, there is likely irreversible change in the macula. 5 In some cases, the CME is refractory to medical treatment including topical corticosteroids, topical nonsteroidal antiinflammatory drugs (NSAIDs), and periocular steroid treatment. Our case was unresponsive to intensive topical corticosteroids and NSAIDs.…”

Topical nepafenac 0.1% alone versus prednisolone acetate 1% as postoperative anti-inflammatory agents in small gauge vitrectomy

“…[13] Topical ketorolac (0.4%)[14] and topical nepafenac (0.1%)[15] are found to be safe and effective in reducing pain and inflammation in patients undergoing vitreoretinal surgery. Naithani et al .,[15] have conducted an investigator-masked, randomized study to evaluate the effect of topical nepafenac on intraocular inflammation, pain, and postoperative macular edema, in patients undergoing vitreoretinal surgery.…”

Pseudophakic Cystoid Macular Edema

“…52 In a followup study, 10 patients were treated with valdecoxib for pseudophakic CME (including the 2 patients treated in the previous study), and all 10 patients showed significant improvement in visual acuity and reduction in edema within ten days of therapy. 53 Nine of the 10 patients had stable acuity for a complete 15 months of follow-up, and 1 patient required a second course of treatment before stable improvement. These findings are somewhat contrasted by a placebo-controlled trial that evaluated celecoxib versus placebo in the prevention of CME after cataract surgery.…”