Successful treatment of calciphylaxis with cinacalcet—an alternative to parathyroidectomy?

Anarchic Deposits: The Intersection of Calciphylaxis and Hemochromatosis, A Case Report

“…On the other hand, calcimimetics increase the sensitivity of the calcium-sensing receptor to calcium decreasing the parathyroid hormone as a consequence. One study reported a very good response to Cinacalect in a patient with calciphylaxis and contraindication for parathyroidectomy, 7 which was not the case in our patient. This observation may be due to the advanced lesions in our patient associated with complete irreversibility.…”

Calcific uraemic arteriolopathy (calciphylaxis) in patients on renal replacement therapy

“…[14] Other treatment strategies include the use of non-calcium-based phosphate binders, bisphosphonates [13,15] and cinacalcet. [16] Intensified haemodialysis, hyperbaric oxygen [17] and sodium thiosulphate, the antioxidant cation chelator [18] used as a component of multimodal therapy, may have contributed to the favourable outcome in some series. [19] In this article we describe 19 patients with ESRD who presented with calciphylaxis, the majority of whom had received a renal transplant.…”

Indikation zur operativen Therapie des renalen Hyperparathyreoidismus

“…Seit 2005 existiert ein deutsches Kalziphylaxieregister, in dem bisher 91 Fälle erfasst wurden. Eine Korrelation zwischen PTH-Wert und Kalziphylaxie konnte nicht dargestellt werden, aber etwa ein Drittel der Patienten wies erhöhte iPTH-Werte auf [38]. Erstes Therapieziel in der Behandlung der Kalziphylaxie ist die Senkung des Kalzium-Phosphat-Produkts, z.…”